Reference on EC 2.5.1.108 - 2-(3-amino-3-carboxypropyl)histidine synthase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Liu, S.; Milne, G.T.; Kuremsky, J.G.; Fink, G.R.; Leppla, S.H.
Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2
Mol. Cell. Biol.
24
9487-9497
2004
Saccharomyces cerevisiae (P32461), Mus musculus (Q9CR25)
Zhu, X.; Dzikovski, B.; Su, X.; Torelli, A.; Zhang, Y.; Ealick, S.; Freed, J.; Lin, H.
Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis
Mol. Biosyst.
7
74-81
2011
Pyrococcus horikoshii (O58832), Pyrococcus horikoshii
Zhang, Y.; Zhu, X.; Torelli, A.T.; Lee, M.; Dzikovski, B.; Koralewski, R.M.; Wang, E.; Freed, J.; Krebs, C.; Ealick, S.E.
Lin, H.: Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme
Nature
465
891-896
2010
Pyrococcus horikoshii (O58832)
Mattheakis, L.C.; Sor, F.; Collier, R.J.
Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene
Gene
132
149-154
1993
Saccharomyces cerevisiae (P32461), Saccharomyces cerevisiae FY251 (P32461)
Webb, T.R.; Cross, S.H.; McKie, L.; Edgar, R.; Vizor, L.; Harrison, J.; Peters, J.; Jackson, I.J.
Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development
J. Cell Sci.
121
3140-3145
2008
Mus musculus
Dong, M.; Horitani, M.; Dzikovski, B.; Pandelia, M.E.; Krebs, C.; Freed, J.H.; Hoffman, B.M.; Lin, H.
An organometallic complex formed by an unconventional radical SAM enzyme
J. Am. Chem. Soc.
138
9755-9758
2016
Pyrococcus horikoshii (O58832), Pyrococcus horikoshii
Abdel-Fattah, W.; Scheidt, V.; Uthman, S.; Stark, M.J.; Schaffrath, R.
Insights into diphthamide, key diphtheria toxin effector
Toxins
5
958-968
2013
Saccharomyces cerevisiae
Fenwick, M.; Dong, M.; Lin, H.; Ealick, S.
The crystal structure of Dph2 in complex with elongation factor 2 reveals the structural basis for the first step of diphthamide biosynthesis
Biochemistry
58
4343-4351
2019
Methanobrevibacter smithii (A5UMY5), Methanobrevibacter smithii DSM 861 (A5UMY5)
Dong, M.; Horitani, M.; Dzikovski, B.; Freed, J.; Ealick, S.; Hoffman, B.; Lin, H.
Substrate-dependent cleavage site selection by unconventional radical S-adenosylmethionine enzymes in diphthamide biosynthesis
J. Am. Chem. Soc.
139
5680-5683
2017
Pyrococcus horikoshii
Dong, M.; Dando, E.; Kotliar, I.; Su, X.; Dzikovski, B.; Freed, J.; Lin, H.
The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis
J. Biol. Inorg. Chem.
24
777-782
2019
Saccharomyces cerevisiae
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