show all | hide all No of entries

Information on EC 2.4.99.2 - beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase

for references in articles please use BRENDA:EC2.4.99.2
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
The enzyme recognizes the sequence beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl (known as type 1 histo-blood group precursor disaccharide) in non-reducing termini of glycan moieties in glycoproteins and glycolipids . When acting on gangloside GM1a, it forms gangloside GD1a .
Specify your search results
Select one or more organisms in this record:
Word Map
  • 2.4.99.2
  • sialylation
  • o-glycans
  • st6gal
  • alpha2,3-sialyltransferase
  • sialylmotifs
  • cmp-sialic
  • st6galnac
  • gm1b
  • 1,3galnac
  • st8sia
  • b4galnt1
  • alpha2,3
The enzyme appears in viruses and cellular organisms
Synonyms
alpha(2,3)-sialyltransferase IV, alpha2,3(N) sialyltransferase, alpha2,3(N)ST, alpha2,3(O) sialyltransferase, alpha2,3(O)ST, CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-(1<->1)-ceramide N-acetylneuraminyltransferase, CMP-N-acetylneuraminate:monosialoganglioside alpha2->3 sialyltransferase, CMP-NANA:GM1 sialyltransferase, CMP-NeuAc:GM1 (Galbeta1,4GalNAc) alpha2-3 sialyltransferase, CMP-NeuAc:GM1 alpha2-3 sialyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R = CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
show the reaction diagram
-
-
-
-
Select items on the left to see more content.