Disease on EC 2.4.1.87 - N-acetyllactosaminide 3-alpha-galactosyltransferase
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DISEASE 
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Breast Neoplasms
Designing a HER2/neu promoter to drive alpha1,3galactosyltransferase expression for targeted anti-alphaGal antibody-mediated tumor cell killing.
Carcinogenesis
Enzymatic basis for changes in fucoganglioside during chemical carcinogenesis. Induction of a specific alpha-fucosyltransferase and status of an alpha-galactosyltransferase in precancerous rat liver and hepatoma.
Carcinoma, Ehrlich Tumor
An alpha-D-galactosyltransferase activity in Ehrlich ascites tumor cells. Biosynthesis and characterization of a trisaccharide (alpha-D-galactose-(1 goes to 3)-N-acetyllactosamine).
Carcinoma, Embryonal
Transcriptional regulation of alpha1,3-galactosyltransferase in embryonal carcinoma cells by retinoic acid. Masking of Lewis X antigens by alpha-galactosylation.
Carcinoma, Hepatocellular
Enzymatic basis for changes in fucoganglioside during chemical carcinogenesis. Induction of a specific alpha-fucosyltransferase and status of an alpha-galactosyltransferase in precancerous rat liver and hepatoma.
Lymphoma
Anti-Gal-mediated targeting of human B lymphoma cells to antigen-presenting cells: a potential method for immunotherapy using autologous tumor cells.
Lymphoma
Enzymatic and organizational difference in expression of a Burkitt lymphoma-associated antigen (globotriaosylceramide) in Burkitt lymphoma and lymphoblastoid cell lines.
Melanoma
Eliciting hyperacute xenograft response to treat human cancer: alpha(1,3) galactosyltransferase gene therapy.
Melanoma
In vivo targeting of vaccinating tumor cells to antigen-presenting cells by a gene therapy method with adenovirus containing the alpha1,3galactosyltransferase gene.
Melanoma
Increased immunogenicity of tumor vaccines complexed with anti-Gal: studies in knockout mice for alpha1,3galactosyltransferase.
Melanoma
Increased immunogenicity of tumor-associated antigen, mucin 1, engineered to express alpha-gal epitopes: a novel approach to immunotherapy in pancreatic cancer.
Melanoma
Reduction of metastatic properties of BL6 melanoma cells expressing terminal fucose(alpha)1-2-galactose after alpha1,2-fucosyltransferase cDNA transfection.
Melanoma, Experimental
Intratumoral injection of alpha-gal glycolipids induces xenograft-like destruction and conversion of lesions into endogenous vaccines.
Neoplasms
An alpha-D-galactosyltransferase activity in Ehrlich ascites tumor cells. Biosynthesis and characterization of a trisaccharide (alpha-D-galactose-(1 goes to 3)-N-acetyllactosamine).
Neoplasms
Autologous tumor vaccines processed to express alpha-gal epitopes: a practical approach to immunotherapy in cancer.
Neoplasms
Designing a HER2/neu promoter to drive alpha1,3galactosyltransferase expression for targeted anti-alphaGal antibody-mediated tumor cell killing.
Neoplasms
Eliciting hyperacute xenograft response to treat human cancer: alpha(1,3) galactosyltransferase gene therapy.
Neoplasms
Human TNF-related apoptosis-inducing ligand-expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses.
Neoplasms
In vivo targeting of vaccinating tumor cells to antigen-presenting cells by a gene therapy method with adenovirus containing the alpha1,3galactosyltransferase gene.
Neoplasms
Increased immunogenicity of tumor vaccines complexed with anti-Gal: studies in knockout mice for alpha1,3galactosyltransferase.
Neoplasms
Intratumoral injection of alpha-gal glycolipids induces xenograft-like destruction and conversion of lesions into endogenous vaccines.
Neoplasms
Regulation of alpha1,3galactosyltransferase expression in pig endothelial cells. Implications for xenotransplantation.
Neoplasms
Synthesis of alpha-gal epitopes (Galalpha1-3Galbeta1-4GlcNAc-R) on human tumor cells by recombinant alpha1,3galactosyltransferase produced in Pichia pastoris.
Neoplasms
The alpha-gal epitope and the anti-Gal antibody in xenotransplantation and in cancer immunotherapy.
Pancreatic Neoplasms
Decrease of human pancreatic cancer cell tumorigenicity by alpha1,3galactosyltransferase gene transfer.
Pancreatic Neoplasms
Relationship between alphaGal epitope expression and decrease of tumorigenicity in pancreatic adenocarcinoma model.
Pheochromocytoma
UDP-galactose:globotriaosylceramide alpha-galactosyltransferase activity in rat pheochromocytoma (PC12h) cells.
Sepsis
Loss of ?-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis.
Teratocarcinoma
Transcriptional regulation of alpha1,3-galactosyltransferase in embryonal carcinoma cells by retinoic acid. Masking of Lewis X antigens by alpha-galactosylation.
Thrombotic Microangiopathies
Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons.
Thrombotic Microangiopathies
The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients.
Thrombotic Microangiopathies
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons.
Trypanosomiasis, African
Specific inhibition of an alpha-galactosyltransferase from Trypanosoma brucei by synthetic substrate analogues.
Venous Thromboembolism
ABO blood group, glycosyltransferase activity and risk of venous thromboembolism.
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