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Disease on EC 2.4.1.69 - type 1 galactoside alpha-(1,2)-fucosyltransferase

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DISEASE
TITLE OF PUBLICATION
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Adenocarcinoma
?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.
Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression.
Enzyme activities in human breast tumor cells and sera.
Adenocarcinoma of Lung
Clinical significance and biological function of fucosyltransferase 2 in lung adenocarcinoma.
Adenoma
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression.
Arthritis, Rheumatoid
Fucosyltransferase 1 mediates angiogenesis in rheumatoid arthritis.
Fucosyltransferase 1 mediates angiogenesis, cell adhesion and rheumatoid arthritis synovial tissue fibroblast proliferation.
Production of soluble human alpha3-fucosyltransferase (FucT VII) by membrane targeting and in vivo proteolysis.
Breast Neoplasms
Alterations in serum glycosyltransferases and 5'-nucleotidase in breast cancer patients.
Analysis of breast cancer-associated glycosphingolipids using electrospray ionization-linear ion trap quadrupole mass spectrometry.
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells.
Immunohistochemical expression of blood group substances and related carbohydrate antigens in breast carcinoma.
Increased fucosylation has a pivotal role in multidrug resistance of breast cancer cells through miR-224-3p targeting FUT4.
MicroRNA-106b targets FUT6 to promote cell migration, invasion, and proliferation in human breast cancer.
[Study on relationship of fucosyltransferase gene types in breast cancer with metastasis and prognosis]
Caliciviridae Infections
A homozygous nonsense mutation (428G-->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections.
Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection.
Mendelian resistance to human norovirus infections.
Norwalk virus RNA is infectious in Mammalian cells.
Susceptibility to winter vomiting disease: a sweet matter.
Carcinogenesis
Elevation of alpha2-->6 sialyltransferase and alpha1-->2 fucosyltransferase activities in human choriocarcinoma.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Carcinoma
alpha1,2Fucosyltransferase increases resistance to apoptosis of rat colon carcinoma cells.
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Altered mRNA expression of glycosyltransferases in human gastric carcinomas.
Beta-1,3-galactosyltransferase and alpha-1,2-fucosyltransferase involved in the biosynthesis of type-1-chain carbohydrate antigens in human colon adenocarcinoma cell lines.
Biosynthesis in vitro of SA-Lex and SA-diLex by alpha 1-3 fucosyltransferases from colon carcinoma cells and embryonic brain tissues.
Biosynthesis of the sialyl-Lex determinant carried by type 2 chain glycosphingolipids (IV3NeuAcIII3FucnLc4, VI3NeuAcV3FucnLc6, and VI3NeuAcIII3V3Fuc2nLc6) in human lung carcinoma PC9 cells.
Biosynthetic pathways for the Leb and Y glycolipids in the gastric carcinoma cell line KATO III as analyzed by a novel assay.
C2-O-sLeX glycoproteins are E-selectin ligands that regulate invasion of human colon and hepatic carcinoma cells.
Correlation between glycoconjugate expression and fucosyltransferase activity in human colorectal carcinoma.
Enhancement of the adhesive and spreading potentials of ovarian carcinoma RMG-1 cells due to increased expression of integrin alpha5beta1 with the Lewis Y-structure on transfection of the alpha1,2-fucosyltransferase gene.
Fucosyltransferase activity in metastasizing and nonmetastasizing rat mammary carcinomas.
Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue.
Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
Increased tumorigenicity of rat colon carcinoma cells after alpha1,2-fucosyltransferase FTA anti-sense cDNA transfection.
Retinoic acid modulation of alpha(1-->2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity.
Role for alpha1,2-fucosyltransferase and histo-blood group antigen H type 2 in resistance of rat colon carcinoma cells to 5-fluorouracil.
Serum fucosylation changes in oral cancer and oral precancerous conditions: alpha-L-fucosidase as a marker.
Simultaneous determination of six tumor markers in patients with prostatic carcinoma and bladder tumors.
The binding characteristics and utilization of Aleuria aurantia, Lens culinaris and few other lectins in the elucidation of fucosyltransferase activities resembling cloned FT VI and apparently unique to colon cancer cells.
Upregulation of Fucosyltransferase 3, 8 and protein O-Fucosyltransferase 1, 2 genes in esophageal cancer stem-like cells (CSLCs).
[alpha1,2-fucosyltransferase gene transfection influences on biological behavior of ovarian carcinoma-derived RMG-I cells]
Carcinoma, Bronchogenic
Serum sialyltransferase and fucosyltransferase activities in patients with bronchial carcinoma.
Carcinoma, Embryonal
Coordinate expression of X and Y haptens during murine embryogenesis.
Developmentally regulated expression of cell surface carbohydrates during mouse embryogenesis.
Molecular cloning and expression of a mouse alpha-1,3 fucosyltransferase gene that shows homology with the human alpha-1,3 fucosyltransferase IV gene.
Purification and properties of N-acetylglucosaminide alpha 1----3-fucosyltransferase from embryonal carcinoma cells.
Carcinoma, Hepatocellular
Altered plasma and tissue fucosyltransferase activities in hepatocellular carcinoma.
An amino acid region at the N-terminus of rat hepatoma alpha1-->2 fucosyltransferase modulates enzyme activity and interaction with lipids: strong preference for glycosphingolipids containing terminal Galbeta1-->3GalNAc-structures.
Comparative study on fucosylation of chicken liver and virus-induced hepatoma Mc-29.
Distribution of glycosyltransferases among Golgi apparatus subfractions from liver and hepatomas of the rat.
Downregulation of microRNA-15b by hepatitis B virus X enhances hepatocellular carcinoma proliferation via fucosyltransferase 2-induced Globo H expression.
Enzymatic basis of sugar structures of alpha-fetoprotein in hepatoma and hepatoblastoma cell lines: correlation with activities of alpha 1-6 fucosyltransferase and N-acetylglucosaminyltransferases III and V.
Enzymic synthesis of a new type of fucose-containing glycolipid with fucosyltransferase of rat ascites hepatoma cell, AH 7974F.
Gene expression of alpha1-6 fucosyltransferase in human hepatoma tissues: a possible implication for increased fucosylation of alpha-fetoprotein.
Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma.
Glycosyltransferases and glycosidases in Morris hepatomas.
Multiple forms of chicken liver and hepatoma Mc-29 microsomal and plasma-membrane sialyl and fucosyltransferases.
Overexpression of alpha1-6 fucosyltransferase in hepatoma cells suppresses intrahepatic metastasis after splenic injection in athymic mice.
Plasma fucosyltransferase activity in patients with hepatocellular carcinoma, with special reference to correlation with fucosylated species of alpha-fetoprotein.
The alpha1-6-fucosyltransferase gene and its biological significance.
The chemical carcinogen-induced enzyme, GDP-fucose: GM1 alpha 1----2 fucosyltransferase in rat liver and hepatoma: modulation by and association with phospholipids.
The enzymatic basis for the conversion of nonfucosylated to fucosylated alpha-fetoprotein by acyclic retinoid treatment in human hepatoma cells: activation of alpha1-6 fucosyltransferase.
Carcinoma, Ovarian Epithelial
Core fucosylation of copper transporter 1 plays a crucial role in cisplatin-resistance of epithelial ovarian cancer by regulating drug uptake.
Carcinoma, Squamous Cell
Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth.
Cardiovascular Diseases
Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study.
Cholangitis, Sclerosing
A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis.
Fucosyltransferase 2: A Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease-A Comprehensive Review.
Knockout of the primary sclerosing cholangitis-risk gene Fut2 causes liver disease in mice.
Choriocarcinoma
Elevation of alpha2-->6 sialyltransferase and alpha1-->2 fucosyltransferase activities in human choriocarcinoma.
Colitis
Altered immune system glycosylation causes colitis in alpha1,2-fucosyltransferase transgenic mice.
Colitis, Ulcerative
Association of fucosyltransferase 2 gene variants with ulcerative colitis in Han and Uyghur patients in China.
Colonic Neoplasms
Beta-1,3-galactosyltransferase and alpha-1,2-fucosyltransferase involved in the biosynthesis of type-1-chain carbohydrate antigens in human colon adenocarcinoma cell lines.
Changes in the invasive and metastatic capacities of HT-29/M3 cells induced by the expression of fucosyltransferase 1.
Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression.
Expression of H type 1 antigen of ABO histo-blood group in normal colon and aberrant expressions of H type 2 and H type 3/4 antigens in colon cancer.
Increased sialyl Lewis A expression and fucosyltransferase activity with acquisition of a high metastatic capacity in a colon cancer cell line.
The binding characteristics and utilization of Aleuria aurantia, Lens culinaris and few other lectins in the elucidation of fucosyltransferase activities resembling cloned FT VI and apparently unique to colon cancer cells.
Transcriptional regulation of fucosyltransferase 1 gene expression in colon cancer cells.
[Fucosyltransferase producing sialyl Le(a) and sialyl Le(x) carbohydrate antigen in gastrointestinal cancer]
Colorectal Neoplasms
Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues.
Correlation between glycoconjugate expression and fucosyltransferase activity in human colorectal carcinoma.
Fucosylated TGF-? receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells.
Involvement of carbohydrate antigen sialyl Lewis(x) in colorectal cancer metastasis.
miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.
Transcriptional activation of fucosyltransferase (FUT) genes using the CRISPR-dCas9-VPR technology reveals potent N-glycome alterations in colorectal cancer cells.
Tumor-related expression of alpha1,2fucosylated antigens on colorectal carcinoma cells and its suppression by cell-mediated priming using sugar acceptors for alpha1,2fucosyltransferase.
Communicable Diseases
Fucosyltransferase Gene Polymorphisms and Lewisb-Negative Status Are Frequent in Swedish Newborns, With Implications for Infectious Disease Susceptibility and Personalized Medicine.
COVID-19
Genetic Polymorphisms in the Host and COVID-19 Infection.
Crohn Disease
Association of FUT2 and ABO with Crohn's disease in Koreans.
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
Cystic Fibrosis
Genetic Polymorphisms in the Host and COVID-19 Infection.
Dermatitis, Atopic
Fucosyltransferase VII-positive, skin-homing T cells in the blood and skin lesions of atopic dermatitis patients.
Diabetes Mellitus, Type 2
Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study.
Digestive System Diseases
Variations in human liver fucosyltransferase activities in hepatobiliary diseases.
Endometrial Neoplasms
[Abnormal expression of carbohydrate chain and its mechanism in endometrial cancer]
Enterocolitis, Necrotizing
A Study on Fucosyltransferase 2 Gene Polymorphism and Secretion Status Related to Neonatal Necrotizing Enterocolitis.
Esophageal Squamous Cell Carcinoma
Upregulation of Fucosyltransferase 3, 8 and protein O-Fucosyltransferase 1, 2 genes in esophageal cancer stem-like cells (CSLCs).
Exostoses
[Primary study on glycan structure in pathopoiesis mechanism of recurrent respiratory papillomatosis]
Fatty Liver
Intestinal ?1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice.
Fetal Growth Retardation
Biallelic Mutations in FUT8 Cause a Congenital Disorder of Glycosylation with Defective Fucosylation.
Gastroenteritis
Clinical significance of the fucosyltransferase 2 (FUT2) secretor status in children hospitalized with acute gastroenteritis in Taiwan.
Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection.
Gastrointestinal Neoplasms
[Fucosyltransferase producing sialyl Le(a) and sialyl Le(x) carbohydrate antigen in gastrointestinal cancer]
Hemochromatosis
Genetic Variants Influencing Biomarkers of Nutrition Are Not Associated with Cognitive Capability in Middle-Aged and Older Adults.
Hepatitis
The alpha1-6-fucosyltransferase gene and its biological significance.
Hepatitis B
Downregulation of microRNA-15b by hepatitis B virus X enhances hepatocellular carcinoma proliferation via fucosyltransferase 2-induced Globo H expression.
Hepatoblastoma
Enzymatic basis of sugar structures of alpha-fetoprotein in hepatoma and hepatoblastoma cell lines: correlation with activities of alpha 1-6 fucosyltransferase and N-acetylglucosaminyltransferases III and V.
Herpes Simplex
Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLex in virus-infected cells.
Induction of sialyl-Lex expression by herpes simplex virus type 1 is dependent on viral immediate early RNA-activated transcription of host fucosyltransferase genes.
Inhibition of protein deacetylation augments herpes simplex virus type 1-activated transcription of host fucosyltransferase genes associated with virus-induced sLex expression.
NF?B-mediated activation of the cellular FUT3, 5 and 6 gene cluster by herpes simplex virus type 1.
Hidradenitis Suppurativa
A new nonsense mutation in the POGLUT1 gene in two sisters with Dowling-Degos disease.
HIV Infections
Decrease of Lewis frequency in HIV-infected patients: possible competition of fucosylated antigens with HIV for binding to DC-SIGN.
Infections
A nonsense mutation (428G-->A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection.
Effects of child and maternal Histo Blood Group Antigen status on symptomatic and asymptomatic enteric infections in early childhood.
Epithelial glycosylation in gut homeostasis and inflammation.
Gastric intrinsic factor deficiency with combined GIF heterozygous mutations and FUT2 secretor variant.
Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection.
Helicobacter pylori serologic status has no influence on the association between fucosyltransferase 2 polymorphism (FUT2 461 G->A) and vitamin B-12 in Europe and West Africa.
Induction of sialyl-Lex expression by herpes simplex virus type 1 is dependent on viral immediate early RNA-activated transcription of host fucosyltransferase genes.
Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1.
Mendelian resistance to human norovirus infections.
New Insight into the Molecular Mechanism of the FUT2 Regulating Escherichia coli F18 Resistance in Weaned Piglets.
Norwalk virus RNA is infectious in Mammalian cells.
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Susceptibility to winter vomiting disease: a sweet matter.
Translational Approach to Induce and Evaluate Verocytotoxic E. coli O138 Based Disease in Piglets.
Use of flow cytometry to monitor infection and recombinant human alpha-1,3/4 fucosyltransferase production in baculovirus infected Sf9 cell cultures.
Virus-induced appearance of the selectin ligand sLeX in herpes simplex virus type 1-infected T-cells: involvement of host and viral factors.
Virus-induced transcriptional activation of host FUT genes associated with neo-expression of Ley in cytomegalovirus-infected and sialyl-Lex in varicella-zoster virus-infected diploid human cells.
Inflammatory Bowel Diseases
Association of Fucosyltransferase 2 Gene Polymorphisms with Inflammatory Bowel Disease in Patients from Southeast China.
Association of Fucosyltransferase 2 Gene Variant with Inflammatory Bowel Diseases: A Meta-Analysis.
Influenza, Human
Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4
Intestinal Neoplasms
[Glycosyltransferase genes for synthesis of Lewis antigens]
Leukemia
Glycosyltransferase activities in leukemic cells from patients and human leukemic cell lines.
Guanosine diphosphate-L-fucose plasma: N-acetylglucosaminide fucosyltransferase as in index of bone marrow hyperplasia after chemotherapy.
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Significance of altered alpha-2-L-fucosyltransferase levels in serum of leukemic patients.
Variation of levels of plasma guanosine diphosphate L-fucose:beta-D-galactosyl alpha-2-L-fucosyltransferase in acute adult leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Electrofocusing patterns of fucosyltransferase activity in plasma of patients with chronic granulocytic leukemia.
Plasma fucosyltransferase as an indicator of imminent blastic crisis.
Leukemia, Myeloid, Acute
Guanosine diphosphate-L-fucose plasma: N-acetylglucosaminide fucosyltransferase as in index of bone marrow hyperplasia after chemotherapy.
Leukemia, T-Cell
Human T-cell leukemia virus-1 encoded Tax protein transactivates alpha 1-->3 fucosyltransferase Fuc-T VII, which synthesizes sialyl Lewis X, a selectin ligand expressed on adult T-cell leukemia cells.
Leukemia-Lymphoma, Adult T-Cell
Human T-cell leukemia virus-1 encoded Tax protein transactivates alpha 1-->3 fucosyltransferase Fuc-T VII, which synthesizes sialyl Lewis X, a selectin ligand expressed on adult T-cell leukemia cells.
Suppression of sialyl Lewis X expression and E-selectin-mediated cell adhesion in cultured human lymphoid cells by transfection of antisense cDNA of an alpha1-->3 fucosyltransferase (Fuc-T VII).
Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element.
Liver Neoplasms
mRNA expression of three glycosyltransferases in human hepatoma tissues.
Lung Diseases
Serum sialyltransferase and fucosyltransferase activities in patients with bronchial carcinoma.
Lung Neoplasms
An integromic signature for lung cancer early detection.
Clinical significance and biological function of fucosyltransferase 2 in lung adenocarcinoma.
Expression of alpha-1,3-fucosyltransferase type IV and VII genes is related to poor prognosis in lung cancer.
Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma.
Lymphoma
Guanosine diphosphate-L-fucose plasma: N-acetylglucosaminide fucosyltransferase as in index of bone marrow hyperplasia after chemotherapy.
Lymphoma, Non-Hodgkin
Guanosine diphosphate-L-fucose plasma: N-acetylglucosaminide fucosyltransferase as in index of bone marrow hyperplasia after chemotherapy.
Melanoma
Enzymatic basis for a lectin-resistant phenotype: increase in a fucosyltransferase in mouse melanoma cells.
Reduction of metastatic properties of BL6 melanoma cells expressing terminal fucose(alpha)1-2-galactose after alpha1,2-fucosyltransferase cDNA transfection.
Selectin ligands on human melanoma cells.
The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.
Melanoma, Experimental
Enzymic properties of an N-acetylglucosaminide 3-alpha-L-fucosyltransferase of a wheat-germ agglutinin-resistant melanoma clone.
Multiple Myeloma
Serum sialyltransferase and fucosyltransferase activities in patients with multiple myeloma.
Neoplasm Metastasis
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma.
Increased sialyl Lewis A expression and fucosyltransferase activity with acquisition of a high metastatic capacity in a colon cancer cell line.
Involvement of carbohydrate antigen sialyl Lewis(x) in colorectal cancer metastasis.
Overexpression of alpha1-6 fucosyltransferase in hepatoma cells suppresses intrahepatic metastasis after splenic injection in athymic mice.
True significance of N-acetylglucosaminyltransferases GnT-III, V and ?1,6 fucosyltransferase in epithelial-mesenchymal transition and cancer.
[Study on relationship of fucosyltransferase gene types in breast cancer with metastasis and prognosis]
Neoplasms
A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis.
A High-Throughput Glycosyltransferase Inhibition Assay for Identifying Molecules Targeting Fucosylation in Cancer Cell-Surface Modification.
alpha(1,3)Fucosyltransferase expression in E-selectin-mediated binding of gastrointestinal tumor cells.
Alteration of liver glycopatterns during cirrhosis and tumor progression induced by HBV.
Alterations in glycosyltransferase activity in human colon cancer.
Alterations in serum glycosyltransferases and 5'-nucleotidase in breast cancer patients.
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.
Carcinoma-related alterations of glycosyltransferases in human tissues.
Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation.
Comprehensive N-glycan profiles of hepatocellular carcinoma reveal association of fucosylation with tumor progression and regulation of FUT8 by microRNAs.
Decrease of human serum fucosyltransferase as an indicator of successful tumor therapy.
Development of fluorescent probes for the detection of fucosylated N-glycans using an Aspergillus oryzae lectin.
Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression.
Enzyme activities in human breast tumor cells and sera.
Evaluation of serum fucosyltransferases in malignancy.
Evaluation of two plasma fucosyltransferases as marker enzymes in non-Hodgkin's lymphoma.
Expression of alpha1-6 fucosyltransferase in rat tissues and human cancer cell lines.
Expression of L-selectin ligands by transformed endothelial cells enhances T cell-mediated rejection.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating ?1, 6-Fucosylation via Wnt/?-Catenin Signaling Pathway.
Fucosylated TGF-? receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells.
Fucosyltransferase 2 induced epithelial-mesenchymal transition via TGF-?/Smad signaling pathway in lung adenocarcinaoma.
Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines.
Fucosyltransferase activity in metastasizing and nonmetastasizing rat mammary carcinomas.
Fucosyltransferase of the peritoneum contributed to the adhesion of cancer cells to the mesothelium.
FUT family mediates the multidrug resistance of human hepatocellular carcinoma via the PI3K/Akt signaling pathway.
Genome-wide DNA methylation identifies trophoblast invasion-related genes: Claudin-4 and Fucosyltransferase IV control mobility via altering matrix metalloproteinase activity.
Glycosyltransferase levels in tumors metastatic to liver and in uninvolved liver tissue.
Human serum fucosyltransferase and tumor therapy.
Immunohistochemical expression of blood group substances and related carbohydrate antigens in breast carcinoma.
Knockdown of fucosyltransferase III disrupts the adhesion of circulating cancer cells to E-selectin without affecting hematopoietic cell adhesion.
miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.
Monoclonal antibody (G10) to a common antigen of human squamous cell carcinoma: binding of the antibody to the H type 2 blood group determinant.
Overexpression of ?2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis.
Peritoneal colonization by human pancreatic cancer cells is inhibited by antisense FUT3 sequence.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Retinoic acid modulation of alpha(1-->2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity.
Screening of enzymatic synthesis and expression of Lewis determinants in human colorectal carcinoma.
Serum levels of glycosyltransferases and related glycoproteins as indicators of cancer: biological and clinical implications.
Structure and expression of the gene encoding secretor-type galactoside 2-alpha-L-fucosyltransferase (FUT2).
The binding characteristics and utilization of Aleuria aurantia, Lens culinaris and few other lectins in the elucidation of fucosyltransferase activities resembling cloned FT VI and apparently unique to colon cancer cells.
The use of con A Sepharose as an affinity adsorbent in a simple assay of serum sialyl and fucosyltransferase and its application in tumour diagnosis.
Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin.
True significance of N-acetylglucosaminyltransferases GnT-III, V and ?1,6 fucosyltransferase in epithelial-mesenchymal transition and cancer.
Tumor-related expression of alpha1,2fucosylated antigens on colorectal carcinoma cells and its suppression by cell-mediated priming using sugar acceptors for alpha1,2fucosyltransferase.
[Elevation of serum fucosyltransferase activities in malignant diseases--a sensitive tumor marker?]
Neuroblastoma
Dorsal root ganglia neuron-specific promoter activity of the rabbit beta-galactoside alpha1,2-fucosyltransferase gene.
Obesity
Intestinal ?1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice.
Ovarian Neoplasms
miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.
[Impact of alpha1,2-Fucosyl Transferase Gene Transfection on Cancer-related Gene Expression Profile of Human Ovarian Cancer Cell Line RMG-1.]
[Inhibitory effect of anti-Lewis y antibody on alpha1,2-fucosyltransferase gene transfected human ovarian cancer cells in vitro.]
Pancreatic Neoplasms
Restoration of alpha(1,2) fucosyltransferase activity decreases adhesive and metastatic properties of human pancreatic cancer cells.
Pancreatitis, Chronic
ABO blood type B and fucosyltransferase 2 non-secretor status as genetic risk factors for chronic pancreatitis.
Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic pancreatitis: a genetic association study.
Genetic susceptibility factors for alcohol-induced chronic pancreatitis.
Prostatic Neoplasms
Lack of selectin-dependent adhesion in prostate cancer cells expressing sialyl Le(x).
Overexpression of ? (1,6) fucosyltransferase associated with aggressive prostate cancer.
Overexpression of ? (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells.
Pulmonary Emphysema
Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling.
Pulmonary Fibrosis
Regulation of the IGF1 signaling pathway is involved in idiopathic pulmonary fibrosis induced by alveolar epithelial cell senescence and core fucosylation.
Small Cell Lung Carcinoma
Biosynthesis of the sialyl-Lex determinant carried by type 2 chain glycosphingolipids (IV3NeuAcIII3FucnLc4, VI3NeuAcV3FucnLc6, and VI3NeuAcIII3V3Fuc2nLc6) in human lung carcinoma PC9 cells.
Stomach Neoplasms
Gene expression of alpha1-6 fucosyltransferase in human hepatoma tissues: a possible implication for increased fucosylation of alpha-fetoprotein.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Purification and cDNA cloning of GDP-L-Fuc:N-acetyl-beta-D-glucosaminide:alpha1-6 fucosyltransferase (alpha1-6 FucT) from human gastric cancer MKN45 cells.
Variation at ABO histo-blood group and FUT loci and diffuse and intestinal gastric cancer risk in a European population.
[Fucosyltransferase producing sialyl Le(a) and sialyl Le(x) carbohydrate antigen in gastrointestinal cancer]
Teratocarcinoma
A fucosyltransferase in teratocarcinoma stem cells. Decreased activity accompanying differentiation to parietal endoderm cells.
Tuberculosis
Fucosyltransferase IV and VII-directed selectin ligand function determines long-term survival in experimental tuberculosis.
type 1 galactoside alpha-(1,2)-fucosyltransferase deficiency
An Alu-mediated large deletion of the FUT2 gene in individuals with the ABO-Bombay phenotype.
Urinary Bladder Neoplasms
Major differences in glycosylation and Fucosyltransferase expression in low-grade versus high-grade bladder cancer cell lines.
Simultaneous determination of six tumor markers in patients with prostatic carcinoma and bladder tumors.
Virus Diseases
Blood group type A secretors are associated with a higher risk of COVID-19 cardiovascular disease complications.
Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4
Susceptibility to winter vomiting disease: a sweet matter.