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BRENDA support

Information on EC 2.4.1.277 - 10-deoxymethynolide desosaminyltransferase

for references in articles please use BRENDA:EC2.4.1.277

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IUBMB Comments

DesVII is the glycosyltransferase responsible for the attachment of dTDP-D-desosamine to 10-deoxymethynolide or narbonolide during the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in the bacterium Streptomyces venezuelae. Activity requires an additional protein partner, DesVIII.

The enzyme appears in viruses and cellular organisms

Synonyms
desvii, desvii/desviii, glycosyltransferase desvii, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose + 10-deoxymethynolide = dTDP + 10-deoxymethymycin
show the reaction diagram
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