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Information on EC 2.4.1.118 - cytokinin 7-beta-glucosyltransferase
for references in articles please use BRENDA:EC2.4.1.118
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EC Tree 2 Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.118 cytokinin 7-beta-glucosyltransferase
IUBMB Comments
Acts on a range of N6-substituted adenines, including zeatin and N6-benzylaminopurine, but not N6-benzyladenine. With some acceptors, 9-β-D-glucosides are also formed.
The enzyme appears in viruses and cellular organisms
Reaction Schemes
showSynonyms
cytokinin 7-glucosyltransferase, glucosyltransferase, uridine diphosphoglucose-zeatin 7-, more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
cytokinin 7-glucosyltransferase
-
-
-
-
glucosyltransferase, uridine diphosphoglucose-zeatin 7-
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-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
UDP-glucose + an N6-alkylaminopurine = UDP + an N6-alkylaminopurine-7-beta-D-glucoside
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hexosyl group transfer
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-
-
-
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SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:N6-alkylaminopurine 7-glucosyltransferase
Acts on a range of N6-substituted adenines, including zeatin and N6-benzylaminopurine, but not N6-benzyladenine. With some acceptors, 9-beta-D-glucosides are also formed.
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CAS REGISTRY NUMBER
COMMENTARY
72103-03-8
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
dihydrozeatin + TDP-glucose
dihydrozeatin 7-beta-D-glucoside + TDP
Substrates: -
Products: -
Products: -
?
kinetin + TDP-glucose
kinetin 7-beta-D-glucoside + TDP
Substrates: -
Products: -
Products: -
?
N6-benzyladenine + TDP-glucose
N6-benzyladenine 7-beta-D-glucoside + TDP
Substrates: -
Products: -
Products: -
?
N6-isopentenyladenine + TDP-glucose
N6-isopentenyladenine 7-beta-D-glucoside + TDP
Substrates: -
Products: -
Products: -
?
TDP-glucose + zeatin
TDP + zeatin 7-beta-D-glucoside
-
Substrates: as effective as UDPglucose
Products: -
Products: -
?
trans-zeatin + TDP-glucose
trans-zeatin 7-beta-D-glucoside + TDP
Substrates: -
Products: -
Products: -
?
UDPglucose + 6-benzylaminopurine
UDP + 6-benzylaminopurine-7-beta-D-glucoside
-
Substrates: activity is 15% higher for 6-benzylaminopurine than for zeatin
Products: -
Products: -
?
UDPglucose + dihydroxyzeatin
UDP + dihydroxyzeatin 7-beta-D-glucoside
-
Substrates: -
Products: -
Products: -
?
UDP-alpha-D-glucose + trans-zeatin
UDP + trans-zeatin 7-beta-D-glucoside
-
Substrates: -
Products: -
Products: -
?
UDP-alpha-D-glucose + trans-zeatin
UDP + trans-zeatin 7-beta-D-glucoside
-
Substrates: i.e. N6-(4-hydroxy-3-methylbut-trans-2-enylamino)purine
Products: + zeatin 9-glucoside
Products: + zeatin 9-glucoside
?
UDPglucose + N6-alkylaminopurine
UDP + N6-alkylaminopurine-7-beta-D-glucoside
-
Substrates: -
Products: -
Products: -
?
UDPglucose + N6-alkylaminopurine
UDP + N6-alkylaminopurine-7-beta-D-glucoside
-
Substrates: involved in regulation of cytokinin activity
Products: -
Products: -
?
additional information
?
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Substrates: no substrate: adenine, guanine, trans-zeatin riboside, 3-isobutyl-1-methylxanthine, 3-methyl-7-pentylamino-pyrazolo(4,3-D)-pyrimidine, o-topolin, m-topolin, thidiazuron
Products: -
Products: -
?
additional information
?
-
Substrates: no substrate: adenine, guanine, trans-zeatin riboside, 3-isobutyl-1-methylxanthine, 3-methyl-7-pentylamino-pyrazolo(4,3-D)-pyrimidine, o-topolin, m-topolin, thidiazuron
Products: -
Products: -
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDPglucose + N6-alkylaminopurine
UDP + N6-alkylaminopurine-7-beta-D-glucoside
-
Substrates: involved in regulation of cytokinin activity
Products: -
Products: -
?
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
Highest Expressing Human Cell Lines
Cell Line LinksPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). U76C1_ARATH
464
0
52360
Swiss-Prot
Secretory Pathway (Reliability: 1)
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Parker, C.W.; Entsch, B.; Letham, D.S.
Inhibitors of two enzymes which metabolize cytokinins
Phytochemistry
25
303-310
1986
Raphanus sativus
-
brenda
Entsch, B.; Letham, D.S.
Enzymic glucosylation of the cytokinin 6-benzylaminopurine
Plant Sci. Lett.
14
205-212
1979
Raphanus sativus
-
brenda
Entsch, B.; Parker, C.W.; Letham, D.S.; Summons, R.E.
Preparation and characterization, using high-performance liquid chromatography, of an enzyme forming glucosides of cytokinins
Biochim. Biophys. Acta
570
124-139
1979
Raphanus sativus
brenda
Hou, B.; Lim, E.K.; Higgins, G.S.; Bowles, D.J.
N-Glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana
J. Biol. Chem.
279
47822-47832
2004
Arabidopsis thaliana (Q9FI99), Arabidopsis thaliana (Q9FIA0)
brenda
EXTERNAL LINKS (specific for EC-Number 2.4.1.118)
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