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Information on EC 2.4.1.110 - tRNA-queuosine beta-mannosyltransferase

for references in articles please use BRENDA:EC2.4.1.110

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EC Tree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.110 tRNA-queuosine beta-mannosyltransferase

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The expected taxonomic range for this enzyme is: Rattus norvegicus

Reaction Schemes

tRNAAsp-O-5''-beta-D-mannosylqueuosine

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

GDP-mannose + tRNAAsp-queuosine = GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine

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REACTION TYPE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

hexosyl group transfer

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SYSTEMATIC NAME

IUBMB Comments

GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase

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CAS REGISTRY NUMBER

COMMENTARY

9055-06-5

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SUBSTRATE

PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

GDPmannose + tRNAAsp-queuosine

GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine

2 entries

GDPmannose + tRNAAsp-queuosine

GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine

Rattus norvegicus

488453

GDPmannose + tRNAAsp-queuosine

GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine

Rattus norvegicus

strict specificity for E. coli tRNAAsp, transfer with concomitant inversion of anomeric configuration at sugar C-1-carbon, no substrates are tRNATyr, tRNAHis or tRNAAsn

488453

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

GDPmannose + tRNAAsp-queuosine

GDP + tRNAAsp-O-5''-beta-D-mannosylqueuosine

Rattus norvegicus

488453

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METALS and IONS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

Mg2+

Rattus norvegicus

requirement

488453

NaCl

Rattus norvegicus

0.1 M NaCl stimulates more than 2fold

488453

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

EDTA

Rattus norvegicus

488453

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pH OPTIMUM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

7.5

Rattus norvegicus

488453

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Rattus norvegicus

male Donryu

488453

brenda

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SOURCE TISSUE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

SOURCE

brenda

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LOCALIZATION

ORGANISM

UNIPROT

COMMENTARY

GeneOntology No.

LITERATURE

SOURCE

brenda

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

partial

Rattus norvegicus

488453

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REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

488453

Okada, N.; Nishimura, S.

Enzymatic synthesis of Q nucleoside containing mannose in the anticodon of tRNA: isolation of a novel mannosyltransferase from a cell-free extract of rat liver

Nucleic Acids Res.

2931-2937

1977

Rattus norvegicus

20603

brenda