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Synonyms
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acyl-acyl carrier protein (acyl-ACP) synthase
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acyltransferase, acyl-[acyl carrier protein]-phospholipid
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an acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = an [acyl-carrier protein] + O-(1,2-diacyl-sn-glycero-3-phospho)ethanolamine
an acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = an [acyl-carrier protein] + O-(1,2-diacyl-sn-glycero-3-phospho)ethanolamine
bifunctional protein exhibits both 2-acylglycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synhtase activities in vitro
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an acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = an [acyl-carrier protein] + O-(1,2-diacyl-sn-glycero-3-phospho)ethanolamine
bifunctional protein exhibits both 2-acylglycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synhtase activities in vitro
an acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = an [acyl-carrier protein] + O-(1,2-diacyl-sn-glycero-3-phospho)ethanolamine
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Acyl group transfer
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acyl-[acyl-carrier protein]:O-(2-acyl-sn-glycero-3-phospho)ethanolamine O-acyltransferase
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acyl-(acyl-carrier protein) + O-(2-acyl-sn-glycero-3-phospho) ethanolamine
(acyl-carrier protein) + O-(1,2-diacyl-sn-glycero-3-phospho) ethanolamine
acyl-(acyl-carrier protein) + O-(2-acyl-sn-glycero-3-phospho) ethanolamine
(acyl-carrier protein) + O-(1,2-diacyl-sn-glycero-3-phospho) ethanolamine
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Substrates: specific for C1-position of glycerol-phosphate backbone, the acyl-component of the acyl-(acyl-carrier-protein) may be 3-hydroxydecanoate, 3-hydroxylaurate, 3-hydroxymyristate and 3-hydroxyoctanoate (tentatively identified)
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acyl-(acyl-carrier protein) + O-(2-acyl-sn-glycero-3-phospho) ethanolamine
(acyl-carrier protein) + O-(1,2-diacyl-sn-glycero-3-phospho) ethanolamine
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Substrates: specific for C1-position of glycerol-phosphate backbone, the acyl-component of the acyl-(acyl-carrier-protein) may be 3-hydroxydecanoate, 3-hydroxylaurate, 3-hydroxymyristate and 3-hydroxyoctanoate (tentatively identified)
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additional information
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no stimulation by coenzyme A, ATP, GTP, UTP, glucosamine 1-phosphate, UDP-N-acetylglucosamine, Triton X-100, lipid A, alkaline treated lipid A or alkaline treated lipid A annealed with Escherichia coli phospholipids
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additional information
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additional information
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additional information
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pI at 4°C: 5.5 (isozyme AT3), 5.6 (isozyme AT2), 6.6 (isozyme AT1)
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5 - 10
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about half-maximal activity at pH 5.0, about 60% of maximal activity at pH 10.0
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squash
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B
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B
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K 12 derivates LCH 25, 26, 28, 55, 56
SwissProt
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greening
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inner
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Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
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30000
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isozyme AT1, gel filtration
40000
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isozyme AT2 and isozyme AT3, gel filtration
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monomer
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1 * 30000, isozyme AT1, 1 * 40000, isozymes AT2 and AT3, SDS-PAGE
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H36A
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mutant lacks 2-acylglycerophosphoethanolamine acyltransferase activity, whereas it retains acyl-acyl carrier protein synthase activity
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100
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inactivation after 2-5 min
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acyl-carrier-protein affinity chromatography
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partial, solubilization by sonic disruption
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expression in Escherichia coli
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Taylor, S.S.; Heath, E.C.
The incorporation of beta-hydroxy fatty acids into a phospholipid of Escherichia coli B
J. Biol. Chem.
244
6605-6616
1969
Escherichia coli, Escherichia coli B / ATCC 11303
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Nishida, I.; Frentzen, M.; Ishizaki, O.; Murata, N.
Purification of isomeric forms of acyl-[acyl-carrier-protein]:glycerol-3-phosphate acyltransferase from greening squash cotyledons
Plant Cell Physiol.
28
1071-1079
1987
Cucurbita moschata
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Jackowski, S.; Jackson, P.D.; Rock, C.O.
Sequence and function of the aas gene in Escherichia coli
J. Biol. Chem.
269
2921-2928
1994
Escherichia coli (P31119), Escherichia coli
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Heath, R.J.; Rock, C.O.
A conserved histidine is essential for glycerolipid acyltransferase catalysis
J. Bacteriol.
180
1425-1430
1998
Escherichia coli
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Transporter Classification Database (TCDB):
4.C.1.1.16
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