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Information on EC 2.3.1.308 - tubulin N-terminal N-acetyltransferase NAT9

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EC Tree
IUBMB Comments
The enzyme, characterized from the fruit fly (Drosophila melanogaster), acetylates the N-terminal of both alpha- and beta-tubulin. The enzyme acts cotranslationally, and can't act on a preformed tubulin alpha/beta heterodimer.
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The expected taxonomic range for this enzyme is: Drosophila melanogaster
Reaction Schemes
+
an N-terminal-L-methionyl-[tubulin]
=
an N-terminal-Nalpha-acetyl-L-methionyl-[tubulin]
+
Synonyms
mnat9, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + an N-terminal-L-methionyl-[tubulin] = an N-terminal-Nalpha-acetyl-L-methionyl-[tubulin] + CoA
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