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Information on EC 2.3.1.233 - 1,3,6,8-tetrahydroxynaphthalene synthase

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IUBMB Comments
Isolated from the fungus Colletotrichum lagenarium , and the bacteria Streptomyces coelicolor [2,3] and Streptomyces peucetius . It only uses malonyl-CoA, without invovement of acetyl-CoA.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
1,3,6,8-tetrahydroxynaphthalene synthase, PhlD, PKS, PKS III, PKS1, RppA, SCO1206, THN synthase, THNS, type III polyketide synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5 malonyl-CoA = 1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO2 + H2O
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PATHWAY SOURCE
PATHWAYS
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