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Information on EC 2.3.1.185 - tropine acyltransferase

for references in articles please use BRENDA:EC2.3.1.185

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IUBMB Comments

This enzyme exhibits absolute specificity for the endo/3α configuration found in tropine as pseudotropine (tropan-3β-ol; see EC 2.3.1.186, pseudotropine acyltransferase) is not a substrate . Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl-CoA and acetyl-CoA being the best substrates. It is probably involved in the formation of the tropane alkaloid littorine, which is a precursor of hyoscyamine .

The enzyme appears in viruses and cellular organisms

Synonyms
tropine:acyl-coa transferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an acyl-CoA + tropine = CoA + an O-acyltropine
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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