Reference on EC 2.3.1.184 - acyl-homoserine-lactone synthase
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Watson, W.T.; Murphy, F.V.I.V.; Gould, T.A.; Jambeck, P.; Val, D.L.; Cronan, J.E., Jr.; Beck von Bodman, S.; Churchill, M.E.A.
Crystallization and rhenium MAD phasing of the acyl-homoserinelactone synthase EsaI
Acta Crystallogr. Sect. D
57
1945-1949
2001
Pantoea stewartii subsp. stewartii
Ulrich, R.L.
Quorum quenching: Enzymatic disruption of N-acylhomoserine lactone-mediated bacterial communication in Burkholderia thailandensis
Appl. Environ. Microbiol.
70
6173-6180
2004
Burkholderia thailandensis
Raychaudhuri, A.; Jerga, A.; Tipton, P.A.
Chemical mechanism and substrate specificity of RhlI, an acylhomoserine lactone synthase from Pseudomonas aeruginosa
Biochemistry
44
2974-2981
2005
Pseudomonas aeruginosa
Kirke, D.F.; Swift, S.; Lynch, M.J.; Williams, P.
The Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner
FEMS Microbiol. Lett.
241
109-117
2004
Aeromonas hydrophila
Hanzelka, B.L.; Parsek, M.R.; Val, D.L.; Dunlap, P.V.; Cronan, J.E., Jr.; Greenberg, E.P.
Acylhomoserine lactone synthase activity of the Vibrio fischeri AinS protein
J. Bacteriol.
181
5766-5770
1999
Aliivibrio fischeri
Gould, T.A.; Herman, J.; Krank, J.; Murphy, R.C.; Churchill, M.E.
Specificity of acyl-homoserine lactone synthases examined by mass spectrometry
J. Bacteriol.
188
773-783
2006
Pantoea stewartii
Kirwan, J.P.; Gould, T.A.; Schweizer, H.P.; Bearden, S.W.; Murphy, R.C.; Churchill, M.E.
Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI
J. Bacteriol.
188
784-788
2006
Yersinia pestis, Yersinia pestis KIM6+
Brader, G.; Sjoblom, S.; Hyytiainen, H.; Sims-Huopaniemi, K.; Palva, E.T.
Altering substrate chain length specificity of an acylhomoserine lactone synthase in bacterial communication
J. Biol. Chem.
280
10403-10409
2005
Pectobacterium carotovorum subsp. carotovorum (Q6R8K9)
Parsek, M.R.; Schaefer, A.L.; Greenberg, E.P.
Analysis of random and site-directed mutations in rhlI, a Pseudomonas aeruginosa gene encoding an acylhomoserine lactone synthase
Mol. Microbiol.
26
301-310
1997
Pseudomonas aeruginosa (P54291), Pseudomonas aeruginosa
Gould, T.A.; Schweizer, H.P.; Churchill, M.E.
Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI
Mol. Microbiol.
53
1135-1146
2004
Pseudomonas aeruginosa
Schaefer, A.L.; Val, D.L.; Hanzelka, B.L.; Cronan, J.E., Jr.; Greenberg, E.P.
Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein
Proc. Natl. Acad. Sci. USA
93
9505-9509
1996
Aliivibrio fischeri
Parsek, M.R.; Val, D.L.; Hanzelka, B.L.; Cronan, J.E.; Greenberg, E.P.
Acyl homoserine-lactone quorum-sensing signal generation
Proc. Natl. Acad. Sci. USA
96
4360-4365
1999
Pseudomonas aeruginosa, Pseudomonas aeruginosa PAO-JP1
Chakrabarti, S.; Sowdhamini, R.
Functional sites and evolutionary connections of acylhomoserine lactone synthases
Protein Eng.
16
271-278
2003
Pantoea stewartii subsp. stewartii
Niu, C.; Clemmer, K.M.; Bonomo, R.A.; Rather, P.N.
Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii
J. Bacteriol.
190
3386-3392
2008
Acinetobacter baumannii (B0FLN1), Acinetobacter baumannii
Steindler, L.; Bertani, I.; De Sordi, L.; Schwager, S.; Eberl, L.; Venturi, V.
LasI/R and RhlI/R quorum sensing in a strain of Pseudomonas aeruginosa beneficial to plants
Appl. Environ. Microbiol.
75
5131-5140
2009
Pseudomonas aeruginosa (A9JPX3), Pseudomonas aeruginosa (A9JPX5), Pseudomonas aeruginosa, Pseudomonas aeruginosa PUPa3 (A9JPX3), Pseudomonas aeruginosa PUPa3 (A9JPX5)
Cao, H.; Yang, M.; Zheng, H.; Zhang, J.; Zhong, Z.; Zhu, J.
Complex quorum-sensing regulatory systems regulate bacterial growth and symbiotic nodulation in Mesorhizobium tianshanense
Arch. Microbiol.
191
283-289
2009
Mesorhizobium tianshanense (B5A462)
Yang, M.; Sun, K.; Zhou, L.; Yang, R.; Zhong, Z.; Zhu, J.
Functional analysis of three AHL autoinducer synthase genes in Mesorhizobium loti reveals the important role of quorum sensing in symbiotic nodulation
Can. J. Microbiol.
55
210-214
2009
Mesorhizobium loti (B0ZTB8), Mesorhizobium loti (B0ZTC1), Mesorhizobium loti, Mesorhizobium loti NZP 2213 (B0ZTB8), Mesorhizobium loti NZP 2213 (B0ZTC1)
Kambam, P.K.; Eriksen, D.T.; Lajoie, J.; Sayut, D.J.; Sun, L.
Altering the substrate specificity of RhlI by directed evolution
ChemBioChem
10
553-558
2009
Pseudomonas aeruginosa
Hussain, M.; Zhang, H.; Xu, J.; Liu, Q.; Jiang, Z.; Zhang, L.
The acyl-homoserine lactone-type quorum-sensing system modulates cell motility and virulence of Erwinia chrysanthemi pv. zeae
J. Bacteriol.
190
1045-1053
2008
Dickeya chrysanthemi (A8D7L4)
Rampioni, G.; Bertani, I.; Pillai, C.R.; Venturi, V.; Zennaro, E.; Leoni, L.
Functional characterization of the quorum sensing regulator RsaL in the plant-beneficial strain Pseudomonas putida WCS358
Appl. Environ. Microbiol.
78
726-734
2012
Pseudomonas aeruginosa, Pseudomonas putida, Pseudomonas putida WCS358
Berger, M.; Neumann, A.; Schulz, S.; Simon, M.; Brinkhoff, T.
Tropodithietic acid production in Phaeobacter gallaeciensis is regulated by N-acyl homoserine lactone-mediated quorum sensing
J. Bacteriol.
193
6576-6585
2011
Phaeobacter inhibens, Phaeobacter inhibens DSM 17395
Lee, Y.; Yeom, J.; Kim, J.; Jung, J.; Jeon, C.O.; Park, W.
Phenotypic and physiological alterations by heterologous acylhomoserine lactone synthase expression in Pseudomonas putida
Microbiology
156
3762-3772
2010
Chromobacterium violaceum
Tsai, C.S.; Winans, S.C.
LuxR-type quorum-sensing regulators that are detached from common scents
Mol. Microbiol.
77
1072-1082
2010
Aliivibrio fischeri, Agrobacterium tumefaciens, Escherichia coli, Pectobacterium carotovorum, Dickeya chrysanthemi, Yersinia pestis, Yersinia pseudotuberculosis, Pseudomonas aeruginosa, Pseudomonas syringae, Serratia marcescens, Serratia sp., Yersinia enterocolitica, Pantoea stewartii, Serratia sp. 39006, Serratia marcescens SS-1
Anbazhagan, D.; Mansor, M.; Yan, G.O.; Md Yusof, M.Y.; Hassan, H.; Sekaran, S.D.
Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp.
PLoS ONE
7
e36696
2012
Acinetobacter sp.
Chung, J.; Goo, E.; Yu, S.; Choi, O.; Lee, J.; Kim, J.; Kim, H.; Igarashi, J.; Suga, H.; Moon, J.S.; Hwang, I.; Rhee, S.
Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc. Natl. Acad. Sci. USA
108
12089-12094
2011
Burkholderia glumae, Burkholderia glumae BGR1
Gao, J.; Ma, A.; Zhuang, X.; Zhuang, G.
An N-acyl homoserine lactone synthase in the ammonia-oxidizing bacterium Nitrosospira multiformis
Appl. Environ. Microbiol.
80
951-958
2014
Nitrosospira multiformis (V5JG72), Nitrosospira multiformis
Britstein, M.; Devescovi, G.; Handley, K.; Malik, A.; Haber, M.; Saurav, K.; Teta, R.; Costantino, V.; Burgsdorf, I.; Gilbert, J.; Sher, N.; Venturi, V.; Steindler, L.
A new N-acyl homoserine lactone synthase in an uncultured symbiont of the red sea sponge Theonella swinhoei
Appl. Environ. Microbiol.
82
1274-1285
2016
uncultured Rhodobacterales bacterium (A0A0U1ZJE3)
Mangwani, N.; Kumari, S.; Das, S.
Involvement of quorum sensing genes in biofilm development and degradation of polycyclic aromatic hydrocarbons by a marine bacterium Pseudomonas aeruginosa N6P6
Appl. Microbiol. Biotechnol.
99
10283-10297
2015
Pseudomonas aeruginosa, Pseudomonas aeruginosa N6P6
Hansen, M.R.; Jakobsen, T.H.; Bang, C.G.; Cohrt, A.E.; Hansen, C.L.; Clausen, J.W.; Le Quement, S.T.; Tolker-Nielsen, T.; Givskov, M.; Nielsen, T.E.
Triazole-containing N-acyl homoserine lactones targeting the quorum sensing system in Pseudomonas aeruginosa
Bioorg. Med. Chem.
23
1638-1650
2015
Escherichia coli, Pseudomonas aeruginosa
How, K.; Hong, K.; Sam, C.; Koh, C.; Yin, W.; Chan, K.
Unravelling the genome of long chain N-acylhomoserine lactone-producing Acinetobacter sp. strain GG2 and identification of its quorum sensing synthase gene
Front. Microbiol.
6
240
2015
Acinetobacter sp., Acinetobacter sp. GG2
Chang, C.; Krishnan, T.; Wang, H.; Chen, Y.; Yin, W.; Chong, Y.; Tan, L.; Chong, T.; Chan, K.
Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target
Sci. Rep.
4
7245
2014
Pseudomonas aeruginosa (P33883), Pseudomonas aeruginosa (P54291), Pseudomonas aeruginosa
Mellbye, B.; Spieck, E.; Bottomley, P.; Sayavedra-Soto, L.
Acyl-homoserine lactone production in nitrifying bacteria of the genera Nitrosospira, Nitrobacter, and Nitrospira identified via a survey of putative quorum-sensing genes
Appl. Environ. Microbiol.
83
e01540-17
2017
Nitrobacter hamburgensis, Nitrobacter vulgaris, Nitrococcus mobilis, Nitrosospira briensis (A0A1I5C818), Nitrosospira briensis, Nitrosospira multiformis, Nitrospira moscoviensis
Yang, Y.; Zhou, M.; Hardwidge, P.; Cui, H.; Zhu, G.
Isolation and characterization of N-acyl homoserine lactone-producing bacteria from cattle rumen and swine intestines
Front. Cell. Infect. Microbiol.
8
155
2018
Aeromonas hydrophila, Pseudomonas aeruginosa, Pseudomonas aeruginosa YZ1, Aeromonas hydrophila YZ2
Jin, L.; Zhang, X.; Shi, H.; Wang, W.; Qiao, Z.; Yang, W.; Du, W.
Identification of a novel N-acyl homoserine lactone synthase, AhyI, in Aeromonas hydrophila and structural basis for its substrate specificity
J. Agric. Food Chem.
68
2516-2527
2020
Aeromonas hydrophila (Q44058), Aeromonas hydrophila, Aeromonas hydrophila HX-3 (Q44058)
Hosoe, A.; Suenaga, T.; Sugi, T.; Iizumi, T.; Nagai, N.; Terada, A.
Complete genome sequence of Pseudomonas putida strain TS312, harboring an HdtS-type N-acyl-homoserine lactone synthase, isolated from a paper mill
Microbiol. Resour. Announc.
9
e00055-20
2020
Pseudomonas putida, Pseudomonas putida TS312
Bauer, J.; Hauck, N.; Christof, L.; Mehnaz, S.; Gust, B.; Gross, H.
The systematic investigation of the quorum sensing system of the biocontrol strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 unveils aurI to be a biosynthetic origin for 3-oxo-homoserine lactones
PLoS ONE
11
e067002
2016
Pseudomonas chlororaphis subsp. aurantiaca (A0A1B1FMK1), Pseudomonas chlororaphis subsp. aurantiaca (M1VJA7), Pseudomonas chlororaphis subsp. aurantiaca (M1VJB2), Pseudomonas chlororaphis subsp. aurantiaca PB-St2 (A0A1B1FMK1), Pseudomonas chlororaphis subsp. aurantiaca PB-St2 (M1VJA7), Pseudomonas chlororaphis subsp. aurantiaca PB-St2 (M1VJB2)
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