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Reference on EC 2.3.1.135 - phosphatidylcholine-retinol O-acyltransferase and Organism(s) Homo sapiens

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
MacDonald, P.N.; Ong, D.E.
A lecithin:retinol acyltransferase activity in human and rat liver
Biochem. Biophys. Res. Commun.
156
157-163
1988
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Ruiz, A.; Winston, A.; Lim, Y.H.; Gilbert, B.A.; Rando, R.R.; Bok, D.
Molecular and biochemical characterization of lecithin retinol acyltransferase
J. Biol. Chem.
274
3834-3841
1999
Bos taurus, Homo sapiens (O95237), Homo sapiens
Manually annotated by BRENDA team
Mondal, M.S.; Ruiz, A.; Bok, D.; Rando, R.R.
Lecithin retinol acyltransferase contains cysteine residues essential for catalysis
Biochemistry
39
5215-5220
2000
Homo sapiens
Manually annotated by BRENDA team
Ruiz, A.; Bok, D.
Molecular characterization of lecithin-retinol acyltransferase
Methods Enzymol.
316
400-413
2000
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Mondal, M.S.; Ruiz, A.; Hu, J.; Bok, D.; Rando, R.R.
Two histidine residues are essential for catalysis by lecithin retinol acyl transferase
FEBS Lett.
489
14-18
2001
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Guo, X.; Knudsen, B.S.; Peehl, D.M.; Ruiz, A.; Bok, D.; Rando, R.R.; Rhim, J.S.; Nanus, D.M.; Gudas, L.J.
Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens
Cancer Res.
62
1654-1661
2002
Homo sapiens
Manually annotated by BRENDA team
Rando, R.R.
Membrane-bound lecithin-retinol acyltransferase
Biochem. Biophys. Res. Commun.
292
1243-1250
2002
Bos taurus, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Jahng, W.J.; Xue, L.; Rando, R.R.
Lecithin retinol acyltransferase is a founder member of a novel family of enzymes
Biochemistry
42
12805-12812
2003
Homo sapiens (O95237)
Manually annotated by BRENDA team
Bok, D.; Ruiz, A.; Yaron, O.; Jahng, W.J.; Ray, A.; Xue, L.; Rando, R.R.
Purification and characterization of a transmembrane domain-deleted form of lecithin retinol acyltransferase
Biochemistry
42
6090-6098
2003
Homo sapiens
Manually annotated by BRENDA team
Xue, L.; Rando, R.R.
Roles of cysteine 161 and tyrosine 154 in the lecithin-retinol acyltransferase mechanism
Biochemistry
43
6120-6126
2004
Homo sapiens (O95237)
Manually annotated by BRENDA team
Zhan, H.C.; Gudas, L.J.; Bok, D.; Rando, R.; Nanus, D.M.; Tickoo, S.K.
Differential expression of the enzyme that esterifies retinol, lecithin:retinol acyltransferase, in subtypes of human renal cancer and normal kidney
Clin. Cancer Res.
9
4897-4905
2003
Homo sapiens
Manually annotated by BRENDA team
Trevino, S.G.; Schuschereba, S.T.; Bowman, P.D.; Tsin, A.
Lecithin:retinol acyltransferase in ARPE-19
Exp. Eye Res.
80
897-900
2005
Homo sapiens, no activity in Gallus gallus
Manually annotated by BRENDA team
Zolfaghari, R.; Ross, A.C.
Cloning, gene organization and identification of an alternative splicing process in lecithin:retinol acyltransferase cDNA from human liver
Gene
341
181-188
2004
Homo sapiens (O95237)
Manually annotated by BRENDA team
Sheren-Manoff, M.; Shin, S.J.; Su, D.; Bok, D.; Rando, R.R.; Gudas, L.J.
Reduced lecithin:retinol acyltransferase expression in human breast cancer
Int. J. Oncol.
29
1193-1199
2006
Homo sapiens
Manually annotated by BRENDA team
Sweeney, M.O.; McGee, T.L.; Berson, E.L.; Dryja, T.P.
Low prevalence of lecithin retinol acyltransferase mutations in patients with Leber congenital amaurosis and autosomal recessive retinitis pigmentosa
Mol. Vis.
13
588-593
2007
Homo sapiens
Manually annotated by BRENDA team
Cai, K.; Gudas, L.J.
Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene
Int. J. Biochem. Cell Biol.
41
546-553
2009
Homo sapiens
Manually annotated by BRENDA team
Nagatsuma, K.; Hayashi, Y.; Hano, H.; Sagara, H.; Murakami, K.; Saito, M.; Masaki, T.; Lu, T.; Tanaka, M.; Enzan, H.; Aizawa, Y.; Tajiri, H.; Matsuura, T.
Lecithin: retinol acyltransferase protein is distributed in both hepatic stellate cells and endothelial cells of normal rodent and human liver
Liver Int.
29
47-54
2009
Homo sapiens (O95237), Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Tang, X.H.; Su, D.; Albert, M.; Scognamiglio, T.; Gudas, L.J.
Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen
Cancer Biol. Ther.
8
1212-1213
2009
Homo sapiens
Manually annotated by BRENDA team
Amann, P.M.; Luo, C.; Owen, R.W.; Hofmann, C.; Freudenberger, M.; Schadendorf, D.; Eichmueller, S.B.; Bazhin, A.V.
Vitamin A metabolism in benign and malignant melanocytic skin cells: importance of lecithin/retinol acyltransferase and RPE65
J. Cell. Physiol.
227
718-728
2012
Homo sapiens
Manually annotated by BRENDA team
Jiang, W.; Napoli, J.L.
Reorganization of cellular retinol-binding protein type 1 and lecithin:retinol acyltransferase during retinyl ester biosynthesis
Biochim. Biophys. Acta
1820
859-869
2012
Homo sapiens
Manually annotated by BRENDA team
Ruiz, A.; Bok, D.
Focus on molecules: lecithin retinol acyltransferase
Exp. Eye Res.
90
186-187
2010
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Bussieres, S.; Cantin, L.; Salesse, C.
Lecithin retinol acyltransferase and its S175R mutant have a similar secondary structure content and maximum insertion pressure but different enzyme activities
Exp. Eye Res.
93
778-781
2011
Homo sapiens
Manually annotated by BRENDA team
Bussieres, S.; Cantin, L.; Desbat, B.; Salesse, C.
Binding of a truncated form of lecithin:retinol acyltransferase and its N- and C-terminal peptides to lipid monolayers
Langmuir
28
3516-3523
2012
Homo sapiens
Manually annotated by BRENDA team
Horchani, H.; Bussires, S.; Cantin, L.; Lhor, M.; Lalibert-Gemme, J.S.; Breton, R.; Salesse C.
Enzymatic activity of lecithin:retinol acyltransferase: a thermostable and highly active enzyme with a likely mode of interfacial activation
Biochim. Biophys. Acta
1844
1128-1836
2014
Homo sapiens (O95237)
Manually annotated by BRENDA team
Hassel, J.C.; Amann, P.M.; Schadendorf, D.; Eichmueller, S.B.; Nagler, M.; Bazhin, A.V.
Lecithin retinol acyltransferase as a potential prognostic marker for malignant melanoma
Exp. Dermatol.
22
757-759
2013
Homo sapiens
Manually annotated by BRENDA team
Gauthier, M.E.; Roy, S.; Cantin, L.; Salesse, C.
Comparison between the enzymatic activity, structure and substrate binding of mouse and human lecithin retinol acyltransferase
Biochem. Biophys. Res. Commun.
519
832-837
2019
Homo sapiens (O95237), Homo sapiens, Mus musculus (Q9JI60), Mus musculus
Manually annotated by BRENDA team
Chelstowska, S.; Widjaja-Adhi, M.A.K.; Silvaroli, J.A.; Golczak, M.
Impact of LCA-associated E14L LRAT mutation on protein stability and retinoid homeostasis
Biochemistry
56
4489-4499
2017
Homo sapiens (O95237)
Manually annotated by BRENDA team
Ajat, M.; Molenaar, M.; Brouwers, J.F.H.M.; Vaandrager, A.B.; Houweling, M.; Helms, J.B.
Hepatic stellate cells retain the capacity to synthesize retinyl esters and to store neutral lipids in small lipid droplets in the absence of LRAT
Biochim. Biophys. Acta
1862
176-187
2017
Homo sapiens (O95237), Mus musculus (Q9JI60)
Manually annotated by BRENDA team
Liang, X.; He, Y.; Chen, M.; Ping, Q.; Chen, J.
The association of lecithin retinol acyltransferase and the 25(OH)D receptor with pediatric overweight and obesity
Eur. J. Clin. Nutr.
73
1626-1629
2019
Homo sapiens (O95237), Homo sapiens
Manually annotated by BRENDA team