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Information on EC 2.3.1.109 - arginine N-succinyltransferase

for references in articles please use BRENDA:EC2.3.1.109

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IUBMB Comments

Also acts on L-ornithine. This is the first enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine . This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC 2.3.1.109 (arginine N-succinyltransferase), EC 3.5.3.23 (N-succinylarginine dihydrolase), EC 2.6.1.81 (succinylornithine transaminase), EC 1.2.1.71 (succinylglutamate-semialdehyde dehydrogenase) and EC 3.5.1.96 (succinylglutamate desuccinylase) [2,6].

The enzyme appears in viruses and cellular organisms

Synonyms
arginine succinyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-arginine degradation II (AST pathway)
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