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Information on EC 2.1.1.230 - 23S rRNA (adenosine1067-2'-O)-methyltransferase

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IUBMB Comments
The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton .
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
nosiheptide-resistance methyltransferase, thiostrepton-resistance methyltransferase, nhr protein, nosiheptide resistance methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + adenosine1067 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyladenosine1067 in 23S rRNA
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