Information on EC 2.1.1.184 - 23S rRNA (adenine2085-N6)-dimethyltransferase

for references in articles please use BRENDA:EC2.1.1.184
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IUBMB Comments
ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine2085.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
ermc', ermc methylase, ermc' methyltransferase, ermc methyltransferase, erythromycin resistance protein, rrna methyltransferase ermc', ermc 23s rrna methyltransferase, ermc 23 s rrna methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 S-adenosyl-L-methionine + adenine2085 in 23S rRNA = 2 S-adenosyl-L-homocysteine + N6-dimethyladenine2085 in 23S rRNA
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