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3 S-adenosyl-L-methionine + glycine = 3 S-adenosyl-L-homocysteine + betaine
S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine
S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
3 S-adenosyl-L-methionine + glycine = 3 S-adenosyl-L-homocysteine + betaine

(overall reaction)
-
3 S-adenosyl-L-methionine + glycine = 3 S-adenosyl-L-homocysteine + betaine
(overall reaction)
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3 S-adenosyl-L-methionine + glycine = 3 S-adenosyl-L-homocysteine + betaine
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-
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S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine

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S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
(1a)
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S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
(1a)
-
-
S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine

-
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S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine
(1c)
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S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine
(1c)
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S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine

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S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
(1b)
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S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
(1b)
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3 S-adenosyl-L-methionine + glycine
3 S-adenosyl-L-homocysteine + betaine
-
Substrates: (overall reaction)
Products: -
?
S-adenosyl-L-methionine + glycine
S-adenosyl-L-homocysteine + N-methylglycine
S-adenosyl-L-methionine + glycine
S-adenosyl-L-homocysteine + sarcosine
S-adenosyl-L-methionine + N,N-dimethylglycine
S-adenosyl-L-homocysteine + betaine
S-adenosyl-L-methionine + N,N-dimethylglycine
S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
S-adenosyl-L-methionine + N-methylglycine
S-adenosyl-L-homocysteine + N,N-dimethylglycine
S-adenosyl-L-methionine + sarcosine
S-adenosyl-L-homocysteine + N,N-dimethylglycine
additional information
?
-
Substrates: no substrate: alanine, methionine
Products: -
?
S-adenosyl-L-methionine + glycine

S-adenosyl-L-homocysteine + N-methylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + glycine
S-adenosyl-L-homocysteine + N-methylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + glycine

S-adenosyl-L-homocysteine + sarcosine
-
Substrates: (1a)
Products: -
?
S-adenosyl-L-methionine + glycine
S-adenosyl-L-homocysteine + sarcosine
Substrates: -
Products: -
?
S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + betaine
-
Substrates: (1c)
Products: -
?
S-adenosyl-L-methionine + N,N-dimethylglycine
S-adenosyl-L-homocysteine + betaine
Substrates: -
Products: -
?
S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N,N-dimethylglycine
S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N-methylglycine

S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N-methylglycine
S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + sarcosine

S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
Substrates: (1b)
Products: -
?
S-adenosyl-L-methionine + sarcosine
S-adenosyl-L-homocysteine + N,N-dimethylglycine
Substrates: -
Products: -
?
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S-adenosyl-L-methionine + glycine
S-adenosyl-L-homocysteine + N-methylglycine
S-adenosyl-L-methionine + N,N-dimethylglycine
S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
S-adenosyl-L-methionine + N-methylglycine
S-adenosyl-L-homocysteine + N,N-dimethylglycine
S-adenosyl-L-methionine + glycine

S-adenosyl-L-homocysteine + N-methylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + glycine
S-adenosyl-L-homocysteine + N-methylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N,N-dimethylglycine
S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N-methylglycine

S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
S-adenosyl-L-methionine + N-methylglycine
S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
Substrates: synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine
Products: -
?
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Lai, M.C.; Wang, C.C.; Chuang, M.J.; Wu, Y.C.; Lee, Y.C.
Effects of substrate and potassium on the betaine-synthesizing enzyme glycine sarcosine dimethylglycine N-methyltransferase from a halophilic methanoarchaeon Methanohalophilus portucalensis
Res. Microbiol.
157
948-955
2006
Methanohalophilus portucalensis, Methanohalophilus portucalensis FDF1
brenda
Kageyama, H.; Tanaka, Y.; Takabe, T.
Biosynthetic pathways of glycinebetaine in Thalassiosira pseudonana; functional characterization of enzyme catalyzing three-step methylation of glycine
Plant Physiol. Biochem.
127
248-255
2018
Thalassiosira pseudonana (B8BQQ3)
brenda