Information on EC 18.104.22.168 - 3'-demethylstaurosporine O-methyltransferasefor references in articles please use BRENDA:EC22.214.171.124
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Catalyses the final step in the biosynthesis of staurosporine, an alkaloidal antibiotic that is a potent inhibitor of protein kinases, especially protein kinase C.
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The enzyme appears in viruses and cellular organisms
3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase, staurosporine synthase, more
S-adenosyl-L-methionine + 3'-demethylstaurosporine = S-adenosyl-L-homocysteine + staurosporine
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