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Reference on EC 1.5.1.7 - saccharopine dehydrogenase (NAD+, L-lysine-forming)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ye, Z.H.; Bhattacharjee, J.K.
Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe
J. Bacteriol.
170
5968-5970
1988
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Schmidt, H.; Bode, R.; Lindner, M.; Birnbaum, D.
Lysine biosynthesis in the yeast Candida maltosa: properties of some enzymes and regulation of the biosynthetic pathway
J. Basic Microbiol.
25
675-681
1985
Candida maltosa, Candida maltosa L4
-
Manually annotated by BRENDA team
Naranjo, L.; Martin de Valmaseda, E.; Banuelos, O.; Lopez, P.; Riano, J.; Casqueiro, J.; Martin, J.F.
Conversion of pipecolic acid into lysine in Penicillium chrysogenum requires pipecolate oxidase and saccharopine reductase: characterization of the lys7 gene encoding saccharopine reductase
J. Bacteriol.
183
7165-7172
2001
Penicillium chrysogenum
Manually annotated by BRENDA team
Schmidt, H.; Bode, R.; Birnbaum, D.
Regulation of the lysine biosynthesis in Pichia guilliermondii
Antonie van Leeuwenhoek
56
337-347
1989
Meyerozyma guilliermondii, Meyerozyma guilliermondii H17
Manually annotated by BRENDA team
Saunders, P.P.; Broquist, H.P.
Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. IV. Saccharopine dehydrogenase
J. Biol. Chem.
241
3435-3440
1966
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.
Chemical mechanism of saccharopine dehydrogenase (NAD+, L-lysine-forming) as deduced from initial rate pH studies
Arch. Biochem. Biophys.
230
553-559
1984
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.
Active-site residues of saccharopine dehydrogenase (NAD+, lysine-forming) from bakers yeast
Biochem. Soc. Trans.
9
281-282
1981
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.; Takata, Y.
Role of arginine residue in saccharopine dehydrogenase (L-lysine forming) from bakers yeast
Biochemistry
20
468-472
1981
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ogawa, H.; Fujioka, M.
The reaction of pyridoxal 5-phosphate with an essential lysine residue of saccharopine dehydrogenase (L-lysine-forming)
J. Biol. Chem.
255
7420-7425
1980
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.; Takata, Y.; Ogawa, H.; Okamoto, M.
The inactivation of saccharopine dehydrogenase (L-lysine-forming) by diethyl pyrocarbonate
J. Biol. Chem.
255
937-942
1980
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.; Takata, Y.
Stereospecificity of hydrogen transfer in the saccharopine dehydrogenase reaction
Biochim. Biophys. Acta
570
210-212
1979
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ogawa, H.; Okamoto, M.; Fujioka, M.
Chemical modification of the active site sulfhydryl group of saccharopine dehydrogenase (L-lysine-forming)
J. Biol. Chem.
254
7030-7035
1979
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Hanke, R.; Hilgenberg, W.
Charakterisierung der Saccharopin-Dehydrogenase aus Phycomyces blakesleeanus
Z. Pflanzenphysiol.
92
23-31
1979
Phycomyces blakesleeanus
-
Manually annotated by BRENDA team
Sugimoto, K.; Fujioka, M.
The reaction of pyruvate with saccharopine dehydrogenase
Eur. J. Biochem.
90
301-307
1978
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ogawa, H.; Fujioka, M.
Purification and characterization of saccharopine dehydrogenase from bakers yeast
J. Biol. Chem.
253
3666-3670
1978
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.
Saccharopine dehydrogenase. Substrate inhibition studies
J. Biol. Chem.
250
8986-8989
1975
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.; Nakatani, Y.
Saccharopine dehydrogenase. A kinetic study of coenzyme binding
J. Biol. Chem.
249
6886-6891
1974
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.; Nakatani, Y.
Saccharopine dehydrogenase. Interaction with substrate analogues
Eur. J. Biochem.
25
301-307
1972
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Fujioka, M.; Nakatani, Y.
A kinetic study of saccharopine dehydrogenase reaction
Eur. J. Biochem.
16
180-186
1970
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Broquist, H.P.
Saccharopine dehydrogenase
Methods Enzymol.
17B
124-129
1971
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Xu, H.; West, A.H.; Cook, P.F.
Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae
Biochemistry
45
12156-12166
2006
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Xu, H.; Alguindigue, S.S.; West, A.H.; Cook, P.F.
A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae
Biochemistry
46
871-882
2007
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Andi, B.; Xu, H.; Cook, P.F.; West, A.H.
Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae
Biochemistry
46
12512-12521
2007
Saccharomyces cerevisiae (P38998)
Manually annotated by BRENDA team
Xu, H.; West, A.H.; Cook, P.F.
Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae
Biochemistry
46
7625-7636
2007
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Burk, D.L.; Hwang, J.; Kwok, E.; Marrone, L.; Goodfellow, V.; Dmitrienko, G.I.; Berghuis, A.M.
Structural studies of the final enzyme in the alpha-aminoadipate pathway-saccharopine dehydrogenase from Saccharomyces cerevisiae
J. Mol. Biol.
373
745-754
2007
Saccharomyces cerevisiae (P38998)
Manually annotated by BRENDA team
Ekanayake, D.K.; Andi, B.; Bobyk, K.D.; West, A.H.; Cook, P.F.
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts
J. Biol. Chem.
285
20756-20768
2010
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Bobyk, K.D.; Kim, S.G.; Kumar, V.P.; Kim, S.K.; West, A.H.; Cook, P.F.
The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH
Arch. Biochem. Biophys.
513
71-80
2011
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kumar, V.P.; West, A.H.; Cook, P.F.
Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae
Arch. Biochem. Biophys.
522
57-61
2012
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kumar, V.P.; Thomas, L.M.; Bobyk, K.D.; Andi, B.; Cook, P.F.; West, A.H.
Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae
Biochemistry
51
857-866
2012
Saccharomyces cerevisiae (P38998)
Manually annotated by BRENDA team
Sheng, X.; Gao, J.; Liu, Y.; Liu, C.
Theoretical study on the proton shuttle mechanism of saccharopine dehydrogenase
J. Mol. Graph. Model.
44
17-25
2013
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Liu, J.; Li, Q.; Jiang, P.; Xu, Z.; Zhang, D.; Zhang, L.; Zhang, M.; Yu, H.; Song, C.; Tan, Q.; Shang, X.; Wang, R.
Overexpression of the saccharopine dehydrogenase gene improves lysine biosynthesis in Flammulina velutipes
J. Basic Microbiol.
59
890-900
2019
Flammulina velutipes (A0A4Y5PV56), Flammulina velutipes, Flammulina velutipes Dan3 (A0A4Y5PV56)
Manually annotated by BRENDA team
Al-Saryi, N.; Al-Hejjaj, M.; Van Roermund, C.; Hulmes, G.; Ekal, L.; Payton, C.; Wanders, R.; Hettema, E.
Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae
Sci. Rep.
7
11868
2017
Saccharomyces cerevisiae (P38998), Saccharomyces cerevisiae ATCC 204508 (P38998)
Manually annotated by BRENDA team