Reference on EC 1.5.1.6 - formyltetrahydrofolate dehydrogenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kutzbach, C.; Stokstad, E.L.R.
10-Formyl tetrahydrofolate:NADP oxidoreductase
Methods Enzymol.
18B
793-798
1971
Gallus gallus, Rattus norvegicus, Sus scrofa
-
Case, G.L.; Kaisaki, P.J.; Steele, R.D.
Resolution of rat liver 10-formyltetrahydrofolate dehydrogenase/hydrolase activities
J. Biol. Chem.
263
10204-10207
1988
Rattus norvegicus
Rios-Orlandi, E.M.; Zarkadas, C.G.; MacKenzie, R.E.
Formyltetrahydrofolate dehydrogenase-hydrolase from pig liver: simultaneous assay of the activities
Biochim. Biophys. Acta
871
24-35
1986
Sus scrofa
Kutzbach, C.; Stokstad, E.L.R.
Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver
Biochem. Biophys. Res. Commun.
30
111-117
1968
Sus scrofa
Min, H.; Shane, B.; Stokstad, E.L.R.
Identification of 10-formyltetrahydrofolate dehydrogenase-hydrolase as a major folate binding protein in liver cytosol
Biochim. Biophys. Acta
967
348-353
1988
Rattus norvegicus, Sus scrofa
Johlin, F.C.; Swain, E.; Smith, C.; Tephly, T.R.
Studies on the mechanism of methanol poisoning: purification and comparison of rat and human liver 10-formyltetrahydrofolate dehydrogenase
Mol. Pharmacol.
35
745-750
1989
Homo sapiens, Rattus norvegicus
Scrutton, M.C.; Beis, I.
Inhibitory effects of histidine and their reversal. The roles of pyruvate carboxylase and N10-formyltetrahydrofolate dehydrogenase
Biochem. J.
177
833-846
1979
Rattus norvegicus
Cook, R.J.; Wagner, C.
Enzymatic activities of rat liver cytosol 10-formyltetrahydrofolate dehydrogenase
Arch. Biochem. Biophys.
321
336-344
1995
Oryctolagus cuniculus, Rattus norvegicus
Wagner, C.; Briggs, W.T.; Horne, D.H.; Cook, R.J.
10-Formyltetrahydrofolate dehydrogenase: Identification of the natural folate ligand, covalent labeling, and partial tryptic digestion
Arch. Biochem. Biophys.
316
141-147
1995
Rattus norvegicus, Sus scrofa
Schirch, D.; Villar, E.; Maras, B.; Barra, D.; Schirch, V.
Domain structure and function of 10-formyltetrahydrofolate dehydrogenase
J. Biol. Chem.
269
24728-24735
1994
Oryctolagus cuniculus
Krupenko, S.A.; Wagner, C.
Aspartate 142 is involved in both hydrolase and dehydrogenase catalytic centers of 10-formyltetrahydrofolate dehydrogenase
J. Biol. Chem.
274
35777-35784
1999
Rattus norvegicus
Krupenko, S.A.; Vlasov, A.P.; Wagner, C.
On the role of conserved histidine 106 in 10-formyltetrahydrofolate dehydrogenase catalysis
J. Biol. Chem.
276
24030-24037
2001
Rattus norvegicus
Krupenko, S.A.; Wagner, C.
Overexpression of functional hydrolase domain of rat liver 10-formyltetrahydrofolate dehydrogenase in Escherichia coli
Protein Expr. Purif.
14
146-152
1998
Rattus norvegicus
Hong, M.; Lee, Y.; Kim, J.W.; Lim, J.S.; Chang, S.Y.; Lee, K.S.; Paik, S.G.; Choe, I.S.
Isolation and characterization of cDNA clone for human liver 10-formyltetrahydrofolate dehydrogenase
Biochem. Mol. Biol. Int.
47
407-415
1999
Homo sapiens
Kim, D.W.; Huang, T.; Schirch, D.; Schirch, V.
Properties of tetrahydropteroylpentaglutamate bound to 10-formyltetrahydrofolate dehydrogenase
Biochemistry
35
15772-15783
1996
Oryctolagus cuniculus
Krupenko, S.A.; Oleinik, N.V.
10-Formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells
Cell Growth Differ.
13
227-236
2002
Homo sapiens, Rattus norvegicus
Krupenko, S.A.; Wagner, C.; Cook, R.J.
Recombinant 10-formyltetrahydrofolate dehydrogenase catalyses both dehydrogenase and hydrolase reactions utilizing the synthetic substrate 10-formyl-5,8-dideazafolate
Biochem. J.
306
651-655
1995
Rattus norvegicus
-
Kim, S.; Park, G.H.; Joo, W.A.; Paik, W.K.; Cook, R.J.; Williams, K.R.
Identification of protein-arginine N-methyltransferase as 10-formyltetrahydrofolate dehydrogenase
J. Biol. Chem.
273
27374-27382
1998
Rattus norvegicus
Krupenko, S.A.; Wagner, C.; Cook, R.J.
Cysteine 707 is involved in the dehydrogenase active site of rat 10-formyltetrahydrofolate dehydrogenase
J. Biol. Chem.
270
519-522
1995
Rattus norvegicus
Champion, K.M.; Cook, R.J.; Tollaksen, S.L.; Giometti, C.S.
Identification of a heritable deficiency of the folate-dependent enzyme 10-formyltetrahydrofolate dehydrogenase in mice
Proc. Natl. Acad. Sci. USA
91
11338-11342
1994
Mus musculus
Martinasevic, M.K.; Green, M.D.; Baron, J.; Tephly, T.R.
Folate and 10-formyltetrahydrofolate dehydrogenase in human and rat retina: Relation to methanol toxicity
Toxicol. Appl. Pharmacol.
141
373-381
1996
Homo sapiens, Rattus norvegicus
Chumanevich, A.A.; Krupenko, S.A.; Davies, C.
The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain
J. Biol. Chem.
279
14355-14364
2004
Rattus norvegicus (P28037)
Reuland, S.N.; Vlasov, A.P.; Krupenko, S.A.
Disruption of a calmodulin central helix-like region of 10-formyltetrahydrofolate dehydrogenase impairs its dehydrogenase activity by uncoupling the functional domains
J. Biol. Chem.
278
22894-22900
2003
Rattus norvegicus (P28037)
Oleinik, N.V.; Krupenko, S.A.
Ectopic expression of 10-formyltetrahydrofolate dehydrogenase in A549 cells induces G1 cell cycle arrest and apoptosis
Mol. Cancer Res.
1
577-588
2003
Homo sapiens
Min, H.; Im, E.S.; Seo, J.S.; Mun, J.A.; Burri, B.J.
Effects of chronic ethanol ingestion and folate deficiency on the activity of 10-formyltetrahydrofolate dehydrogenase in rat liver
Alcohol. Clin. Exp. Res.
29
2188-2193
2005
Rattus norvegicus
Oleinik, N.V.; Krupenko, N.I.; Priest, D.G.; Krupenko, S.A.
Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression
Biochem. J.
391
503-511
2005
Homo sapiens
Kim, H.S.; Kim, J.M.; Roh, K.B.; Lee, H.H.; Kim, S.J.; Shin, Y.H.; Lee, B.L.
Rat liver 10-formyltetrahydrofolate dehydrogenase, carbamoyl phosphate synthetase 1 and betaine homocysteine S-methytransferase were co-purified on Kunitz-type soybean trypsin inhibitor-coupled sepharose CL-4B
J. Biochem. Mol. Biol.
40
604-609
2007
Rattus norvegicus
Tsybovsky, Y.; Donato, H.; Krupenko, N.I.; Davies, C.; Krupenko, S.A.
Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases
Biochemistry
46
2917-2929
2007
Rattus norvegicus
Donato, H.; Krupenko, N.I.; Tsybovsky, Y.; Krupenko, S.A.
10-formyltetrahydrofolate dehydrogenase requires a 4-phosphopantetheine prosthetic group for catalysis
J. Biol. Chem.
282
34159-34166
2007
Rattus norvegicus
McNeil, C.J.; Hay, S.M.; Rucklidge, G.J.; Reid, M.; Duncan, G.; Maloney, C.A.; Rees, W.D.
Disruption of lipid metabolism in the liver of the pregnant rat fed folate-deficient and methyl donor-deficient diets
Br. J. Nutr.
99
262-271
2008
Rattus norvegicus (P28037)
Strickland, K.C.; Hoeferlin, L.A.; Oleinik, N.V.; Krupenko, N.I.; Krupenko, S.A.
Acyl carrier protein-specific 4-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase
J. Biol. Chem.
285
1627-1633
2010
Homo sapiens
Krupenko, N.I.; Dubard, M.E.; Strickland, K.C.; Moxley, K.M.; Oleinik, N.V.; Krupenko, S.A.
ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase
J. Biol. Chem.
285
23056-23063
2010
Homo sapiens (O75891), Homo sapiens (Q3SY69), Homo sapiens
Ghose, S.; Oleinik, N.V.; Krupenko, N.I.; Krupenko, S.A.
10-formyltetrahydrofolate dehydrogenase-induced c-Jun-NH2-kinase pathways diverge at the c-Jun-NH2-kinase substrate level in cells with different p53 status
Mol. Cancer Res.
7
99-107
2009
Homo sapiens
Chang, W.N.; Lin, H.C.; Fu, T.F.
Zebrafish 10-formyltetrahydrofolate dehydrogenase is similar to its mammalian isozymes for its structural and catalytic properties
Protein Expr. Purif.
72
217-222
2010
Danio rerio (E3NZ06), Danio rerio
Strickland, K.C.; Krupenko, N.I.; Dubard, M.E.; Hu, C.J.; Tsybovsky, Y.; Krupenko, S.A.
Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase
Chem. Biol. Interact.
191
129-136
2011
Homo sapiens
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