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Information on EC 1.5.1.47 - dihydromethanopterin reductase [NAD(P)+]

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IUBMB Comments
The enzyme, characterized from the bacterium Methylobacterium extorquens, is involved in biosynthesis of dephospho-tetrahydromethanopterin. The specific activity with NADH is 15% of that with NADPH at the same concentration . It does not reduce 7,8-dihydrofolate (cf. EC 1.5.1.3, dihydrofolate reductase).
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The enzyme appears in viruses and cellular organisms
Synonyms
dihydromethanopterin reductase, DmrA, H2MPT reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5,6,7,8-tetrahydromethanopterin + NAD(P)+ = 7,8-dihydromethanopterin + NAD(P)H + H+
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PATHWAY SOURCE
PATHWAYS
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