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Information on EC 1.5.1.27 - 1,2-dehydroreticulinium reductase (NADPH)

for references in articles please use BRENDA:EC1.5.1.27
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IUBMB Comments
Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a direct precursor of morphinan alkaloids in the poppy plant. The enzyme does not catalyse the reverse reaction to any significant extent under physiological conditions.
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The expected taxonomic range for this enzyme is: Papaver
Synonyms
storr, 1,2-dehydroreticuline reductase, reticuline epimerase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-reticuline + NADP+ = 1,2-dehydroreticulinium + NADPH + H+
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