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Information on EC 1.3.1.95 - acrylyl-CoA reductase (NADH)

for references in articles please use BRENDA:EC1.3.1.95

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IUBMB Comments

Contains FAD. The reaction is catalysed in the opposite direction to that shown. The enzyme from the bacterium Clostridium propionicum is a complex that includes an electron-transfer flavoprotein (ETF). The ETF is reduced by NADH and transfers the electrons to the active site. Catalyses a step in a pathway for L-alanine fermentation to propanoate . cf. EC 1.3.1.84, acrylyl-CoA reductase (NADPH).

The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes

Synonyms
Acr, acryloyl-CoA reductase, acryloyl-CoA reductase (NADPH), acryloyl-coenzyme A reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
propanoyl-CoA + NAD+ = acryloyl-CoA + NADH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
pyruvate fermentation to propanoate II (acrylate pathway)
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