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Information on EC 1.3.1.119 - chlorobenzene dihydrodiol dehydrogenase

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IUBMB Comments
This bacterial enzyme can transform various dihydrodiols of chlorobenzenes into the respective catechols, including the dihydrodiols of mono-, di-, tri-, and tetra-chlorinated benzenes. It also accepts the dihydrodiols of various chlorotoluenes. Substrates for the enzyme are generated by the broad spectrum EC 1.14.12.26, chlorobenzene dioxygenase.
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The enzyme appears in viruses and cellular organisms
Synonyms
3,6-dichlorobenzene DDH, cbzB, CDD, chlorobenzene cis-dihydrodiol dehydrogenase, cis-chlorobenzene dihydrodiol dehydrogenase, TcbB, tecB, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD+ = 3-chlorocatechol + NADH + H+
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