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Information on EC 1.23.1.1 - (+)-pinoresinol reductase

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EC Tree
     1 Oxidoreductases
         1.23 Reducing C-O-C group as acceptor
             1.23.1 With NADH or NADPH as donor
                1.23.1.1 (+)-pinoresinol reductase
IUBMB Comments
The reaction is catalysed in vivo in the opposite direction to that shown. A multifunctional enzyme that further reduces the product to the lignan (-)-secoisolariciresinol [EC 1.23.1.2, (+)-lariciresinol reductase]. Isolated from the plants Forsythia intermedia [1,2], Thuja plicata (western red cedar) , Linum perenne (perennial flax) and Linum corymbulosum . The 4-pro-R hydrogen of NADH is transferred to the 7-pro-R position of lariciresinol .
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
(+)-pinoresinol reductase, (+)-pinoresinol-(+)-lariciresinol reductase, (+)-pinoresinol/(+)-lariciresinol, (+)-pinoresinol/(+)-lariciresinol reductase, (+)pinoresinol-(+)lariciresinol reductase, bi-functional pinoresinol/lariciresinol reductase, bifunctional pinoresinol-lariciresinol reductase 2, LuPLR2, More, pinoresinol reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+)-lariciresinol + NADP+ = (+)-pinoresinol + NADPH + H+
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