Reference on EC 1.2.1.88 - L-glutamate gamma-semialdehyde dehydrogenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Small, W.C.; Jones, M.E.
Pyrroline 5-carboxylate dehydrogenase of the mitochondrial matrix of rat liver. Purification, physical and kinetic characteristics
J. Biol. Chem.
265
18668-18672
1990
Homo sapiens, Rattus norvegicus
Hull, E.P.; Green, P.M.; Arst, H.N.; Scazzocchio, C.
Cloning and physical characterization of the L-proline catabolism gene cluster of Aspergillus nidulans
Mol. Microbiol.
3
553-559
1989
Aspergillus nidulans
Isobe, K.; Matsuzawa, T.; Soda, K.
Crystallization and characterization of 1-pyrroline-5-carboxylate dehydrogenase from Bacillus sphaericus
Agric. Biol. Chem.
51
1947-1953
1987
Geobacillus stearothermophilus, [Bacillus] caldotenax, Lysinibacillus sphaericus, Geobacillus thermodenitrificans
-
Small, C.; Jones, M.E.
A specific radiochemical assay for pyrroline-5-carboxylate dehydrogenase
Anal. Biochem.
161
380-386
1987
Rattus norvegicus
Thompson, S.G.; Wong, P.T.H.; Leong, S.F.; McGeer, E.G.
Regional distribution in rat brain of 1-pyrroline-5-carboxylate dehydrogenase and its localization to specific glial cells
J. Neurochem.
45
1791-1796
1985
Rattus norvegicus
Menzel, R.; Roth, J.
Enzymatic properties of the purified putA protein from Salmonella typhimurium
J. Biol. Chem.
256
9762-9766
1981
Salmonella enterica subsp. enterica serovar Typhimurium
Menzel, R.; Roth, J.
Purification of the putA gene product. A bifunctional membrane-bound protein from Salmonella typhimurium responsible for the two-step oxidation of proline to glutamate
J. Biol. Chem.
256
9755-9761
1981
Salmonella enterica subsp. enterica serovar Typhimurium
Brandriss, M.C.; Magasanik, B.
Proline: an essential intermediate in arginine degradation in Saccharomyces cerevisiae
J. Bacteriol.
143
1403-1410
1980
Saccharomyces cerevisiae
Herzfeld, A.; Mezl, V.A.; Knox, W.E.
Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues
Biochem. J.
166
95-103
1977
Rattus norvegicus
Boggess, S.F.; Paleg, L.G.; Aspinall, D.
DELTA1-pyrroline-5-carboxylic acid dehydrogenase in barley, a proline-accumulating species
Plant Physiol.
56
259-262
1975
Hordeum vulgare subsp. vulgare
Stewart, C.R.; Lai, E.Y.
DELTA1-pyrroline-5-carboxylic acid dehydrogenase in mitochondrial preparations from plant seedlings
Plant Sci. Lett.
3
173-181
1974
Ricinus communis, Cucurbita maxima, Pisum sativum, Zea mays
-
Lundgren, D.W.; Ogur, M.
Inhibition of yeast 1 -pyrroline-5-carboxylate dehydrogenase by common amino acids and the regulation of proline catabolism
Biochim. Biophys. Acta
297
246-257
1973
Saccharomyces sp.
Dendinger, S.; Brill, W.J.
Effect of the proline analogue baikiain on proline metabolism in Salmonella typhimurium
J. Bacteriol.
112
1134-1141
1972
Salmonella enterica subsp. enterica serovar Typhimurium
Lundgren, D.; Ogur, M.
Amino acid inhibition of a 1 -pyrroline-5-carboxylate dehydrogenase preparation from beef kidney mitochondria
Biochem. Biophys. Res. Commun.
49
147-149
1972
Bos taurus
Strecker, H.J.
DELTA1-pyrroline-5-carboxylate dehydrogenase (ox liver) (oxidation of DELTA1-pyrroline-5-carboxylate to glutamate)
Methods Enzymol.
17B
262-265
1971
Bos taurus
-
Brunner, G.; Neupert, W.
Localisation of proline oxidase and DELTA1-pyrroline-5-carboxylic acid dehydrogenase in rat liver
FEBS Lett.
3
283-286
1969
Rattus norvegicus
Adams, E.; Goldstone, A.
Hydroxyproline metabolism. IV. Enzymatic synthesis of gamma-hydroxyglutamate from DELTA1-pyrroline-3-hydroxy-5-carboxylate
J. Biol. Chem.
235
3504-3512
1960
Bos taurus
Strecker, H.J.
The interconversion of glutamic acid and proline
J. Biol. Chem.
235
3218-3223
1960
Bos taurus
-
Brandriss, M.C.
Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT2 gene
Mol. Cell. Biol.
3
1846-1856
1983
Saccharomyces cerevisiae
Schaap, P.J.; Muller, Y.; Sonnenberg, A.S.; van Griensven, L.J.; Visser, J.
The Agaricus bisporus pruA gene encodes a cytosolic delta 1-pyrroline-5-carboxylate dehydrogenase which is expressed in fruit bodies but not in gill tissue
Appl. Environ. Microbiol.
63
57-62
1997
Agaricus bisporus
Smith, D.D.S.; Wood, N.J.; Hodgson, D.A.
Interaction between primary and secondary metabolism in Streptomyces coelicolor A3(2): role of pyrroline-5-carboxylate dehydrogenase
Microbiology
141
1739-1744
1995
Streptomyces coelicolor, Streptomyces coelicolor A3(2)
-
Forlani, G.; Scainelli, D.; Nielsen, E.
Two DELTA1-pyrroline-5-carboxylate dehydrogenase isoforms are expressed in cultured Nicotiana plumbaginifolia cells and are differentially modulated during the culture growth cycle
Planta
202
242-248
1997
Nicotiana plumbaginifolia
-
Forlani, G.; Mangiagalli, A.; Pinter, C.; Nielsen, E.
Expression of DELTA1-pyrroline-5-carboxylate dehydrogenase and proline/arginine homeostasis in Solanum tuberosum
Physiol. Plant.
110
22-27
2000
Daucus carota, Solanum lycopersicum, Nicotiana plumbaginifolia, Solanum glaucophyllum, Solanum melongena, Solanum tuberosum, Arthrospira platensis
-
Forlani, G.; Scainelli, D.; Nielsen, E.
DELTA1-Pyrroline-5-carboxylate dehydrogenase from cultured cells of potato. Purification and properties
Plant Physiol.
113
1413-1418
1997
Solanum tuberosum
Hu, C.A.; Lin, W.W.; Valle, D.
Cloning characterization, and expression of cDNAs encoding human DELTA1-pyrroline-5-carboxylate dehydrogenase
J. Biol. Chem.
271
9795-9800
1996
Homo sapiens (P30038), Homo sapiens
Fahmy, A.S.; Mohamed, S.A.; Girgis, R.B.; Abdel-Ghaffar, F.A.
Enzymes of DELTA1-pyrroline-5-carboxylate metabolism in the camel tick Hyalomma dromedarii during embryogenesis. Purification and characterization of DELTA1-pyrroline-5-carboxylate dehydrogenases
Comp. Biochem. Physiol. B
118
229-237
1997
Hyalomma dromedarii
Donald, S.P.; Sun, X.Y.; Hu, C.A.A.; Yu, J.; Mei, J.M.; Valle, D.; Phang, J.M.
Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species
Cancer Res.
61
1810-1815
2001
Homo sapiens
Haslett, M.R.; Pink, D.; Walters, B.; Brosnan, M.E.
Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver
Biochim. Biophys. Acta
1675
81-86
2004
Rattus norvegicus
Inagaki, E.; Ohshima, N.; Takahashi, H.; Kuroishi, C.; Yokoyama, S.; Tahirov, T.H.
Crystal structure of Thermus thermophilus DELTA1-pyrroline-5-carboxylate dehydrogenase
J. Mol. Biol.
362
490-501
2006
Thermus thermophilus
Tizzano, M.; Sbarbati, A.
Is rat LRRP Ba1-651 a Delta-1-pyrroline-5-carboxylate dehydrogenase activated by changes in the concentration of sweet molecules?
Med. Hypotheses
68
864-867
2007
Rattus norvegicus
Gao, C.; Han, B.
Evolutionary and expression study of the aldehyde dehydrogenase (ALDH) gene superfamily in rice (Oryza sativa)
Gene
431
86-94
2009
Oryza sativa, Oryza sativa (Q0DHN6)
Miller, G.; Honig, A.; Stein, H.; Suzuki, N.; Mittler, R.; Zilberstein, A.
Unraveling delta1-pyrroline-5-carboxylate-proline cycle in plants by uncoupled expression of proline oxidation enzymes
J. Biol. Chem.
284
26482-26492
2009
Arabidopsis thaliana (Q8VZC3)
Wu, G.; Bazer, F.W.; Davis, T.A.; Kim, S.W.; Li, P.; Marc Rhoads, J.; Carey Satterfield, M.; Smith, S.B.; Spencer, T.E.; Yin, Y.
Arginine metabolism and nutrition in growth, health and disease
Amino Acids
37
153-168
2009
Mammalia
Brown, E.D.; Wood, J.M.
Redesigned purification yields a fully functional PutA protein dimer from Escherichia coli
J. Biol. Chem.
267
13086-13092
1992
Escherichia coli (P09546), Escherichia coli
Pemberton, T.A.; Tanner, J.J.
Structural basis of substrate selectivity of delta(1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): semialdehyde chain length
Arch. Biochem. Biophys.
538
34-40
2013
Mus musculus (Q8CHT0), Mus musculus
Pemberton, T.A.; Srivastava, D.; Sanyal, N.; Henzl, M.T.; Becker, D.F.; Tanner, J.J.
Structural studies of yeast delta(1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): active site flexibility and oligomeric state
Biochemistry
53
1350-1359
2014
Saccharomyces cerevisiae (P07275), Saccharomyces cerevisiae, Homo sapiens (P30038), Homo sapiens
Monteoliva, M.I.; Rizzi, Y.S.; Cecchini, N.M.; Hajirezaei, M.R.; Alvarez, M.E.
Context of action of proline dehydrogenase (ProDH) in the hypersensitive response of Arabidopsis
BMC Plant Biol.
14
21
2014
Arabidopsis thaliana (Q8VZC3)
Ion, B.; Aboelnga, M.; Gauld, J.
Insights from molecular dynamics on substrate binding and effects of active site mutations in delta1-pyrroline-5-carboxylate dehydrogenase
Can. J. Chem.
94
1151-1162
2016
Homo sapiens (P30038)
-
Gong, M.; Tang, C.; Zhu, C.
Cloning and expression of delta-1-pyrroline-5-carboxylate dehydrogenase in Escherichia coli DH5alpha improves phosphate solubilization
Can. J. Microbiol.
60
761-765
2014
Penicillium oxalicum, Penicillium oxalicum I1
Forlani, G.; Bertazzini, M.; Zarattini, M.; Funck, D.
Functional characterization and expression analysis of rice delta(1)-pyrroline-5-carboxylate dehydrogenase provide new insight into the regulation of proline and arginine catabolism
Front. Plant Sci.
6
591
2015
Oryza sativa
Moxley, M.A.; Sanyal, N.; Krishnan, N.; Tanner, J.J.; Becker, D.F.
Evidence for hysteretic substrate channeling in the proline dehydrogenase and delta1-pyrroline-5-carboxylate dehydrogenase coupled reaction of proline utilization A (PutA)
J. Biol. Chem.
289
3639-3651
2014
Escherichia coli (P09546), Escherichia coli
Mantilla, B.S.; Paes, L.S.; Pral, E.M.; Martil, D.E.; Thiemann, O.H.; Fernandez-Silva, P.; Bastos, E.L.; Silber, A.M.
Role of delta1-pyrroline-5-carboxylate dehydrogenase supports mitochondrial metabolism and host-cell invasion of Trypanosoma cruzi
J. Biol. Chem.
290
7767-7790
2015
Trypanosoma cruzi (Q4DRT8), Trypanosoma cruzi CL Brener (Q4DRT8)
Luo, M.; Singh, R.K.; Tanner, J.J.
Structural determinants of oligomerization of delta(1)-pyrroline-5-carboxylate dehydrogenase: identification of a hexamerization hot spot
J. Mol. Biol.
425
3106-3120
2013
Bacillus licheniformis (Q65NN2), Thermus thermophilus (Q72IB9), Thermus thermophilus, Halalkalibacterium halodurans (Q9K9B2), Deinococcus radiodurans (Q9RW56), Deinococcus radiodurans, Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 (Q72IB9), Deinococcus radiodurans DSM 20539 (Q9RW56), Halalkalibacterium halodurans DSM 18197 (Q9K9B2), Bacillus licheniformis DSM 13 (Q65NN2)
Li, B.; Cai, D.; Hu, S.; Zhu, A.; He, Z.; Chen, S.
Enhanced synthesis of poly gamma glutamic acid by increasing the intracellular reactive oxygen species in the Bacillus licheniformis delta1-pyrroline-5-carboxylate dehydrogenase gene ycgN-deficient strain
Appl. Microbiol. Biotechnol.
102
10127-10137
2018
Bacillus licheniformis
Campbell, A.C.; Bogner, A.N.; Mao, Y.; Becker, D.F.; Tanner, J.J.
Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A
Arch. Biochem. Biophys.
698
108727
2021
Sinorhizobium meliloti (F7X6I3), Sinorhizobium meliloti SM11 (F7X6I3)
Korasick, D.A.; Koncitikova, R.; Kopecna, M.; Hajkova, E.; Vigouroux, A.; Morera, S.; Becker, D.F.; Sebela, M.; Tanner, J.J.; Kopecny, D.
Structural and biochemical characterization of aldehyde dehydrogenase 12, the last enzyme of proline catabolism in plants
J. Mol. Biol.
431
576-592
2019
Zea mays (A0A2H4PMI3), Zea mays, Physcomitrium patens (A9S190), Physcomitrium patens
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