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The Euglena enzyme can also use FAD or methylviologen as acceptor, more slowly. The enzyme is inhibited by oxygen.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
pyruvate dehydrogenase, pyruvate:nadp+ oxidoreductase, cppno, more
pyruvate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH
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Transporter Classification Database (TCDB):