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Information on EC 1.14.99.4 - progesterone monooxygenase

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EC Tree
IUBMB Comments
Has a wide specificity. A single enzyme from ascomycete the Neonectria radicicola (EC 1.14.13.54 ketosteroid monooxygenase) catalyses both this reaction and that catalysed by EC 1.14.99.12 androst-4-ene-3,17-dione monooxygenase.
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Word Map
  • 1.14.99.4
  • olfactory
  • steroid
  • cyp2a5
  • lauric
  • p450cam
  • chemosensory
  • mucosa-specific
  • olfactory-specific
  • tissue-selective
  • nutrition
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
cyp2g1, progesterone hydroxylase, progesterone monooxygenase, 17alpha-progesterone hydroxylase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
progesterone + reduced acceptor + O2 = testosterone acetate + acceptor + H2O
show the reaction diagram
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