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Synonyms
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EC 1.14.1.10
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formerly
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estradiol 6beta-hydroxylase
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oxygenase, estradiol 6beta-mono-
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estradiol-17beta + reduced acceptor + O2 = 6beta-hydroxyestradiol-17beta + acceptor + H2O
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estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)
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estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
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Substrates: -
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estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
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Substrates: estradiol-17beta i.e. estra-1,3,5(10)-triene-3,17beta-diol
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estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
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Substrates: -
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estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
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Substrates: estradiol-17beta i.e. estra-1,3,5(10)-triene-3,17beta-diol
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NADPH
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Highest Expressing Human Cell Lines
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Muller, G.C.; Rumney, G.
Formation of 6beta-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes
J. Am. Chem. Soc.
79
1004-1005
1957
Mus musculus
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brenda
Hokama, Y.; Koga, N.; Yoshimura, H.
Purification and characterization of two forms of chicken liver cytochrome P-450 induced by 3,4,5,3',4'-pentachlorobiphenyl
J. Biochem.
104
355-361
1988
Gallus gallus
brenda
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