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Information on EC 1.14.99.10 - steroid 21-monooxygenase

for references in articles please use BRENDA:EC1.14.99.10

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Please check here for current data: EC 1.14.14.16
transferred to EC 1.14.14.16
IUBMB Comments

Requires NADPH and EC 1.6.2.4, NADPH—hemoprotein reductase. A heme-thiolate protein (P-450) enzyme responsible for the conversion of progesterone and 17α-hydroxyprogesterone to their respective 21-hydroxylated derivatives, 11-deoxycorticosterone and 11-deoxycortisol. Involved in the biosynthesis of the hormones aldosterone and cortisol.

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