Reference on EC 1.14.19.9 - tryptophan 7-halogenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dong, C.; Kotzsch, A.; Dorward, M.; van Pee, K.H.; Naismith, J.H.
Crystallization and X-ray diffraction of a halogenating enzyme, tryptophan 7-halogenase, from Pseudomonas fluorescens
Acta Crystallogr. Sect. D
60
1438-1440
2004
Pseudomonas fluorescens
Unversucht, S.; Hollmann, F.; Schmid, A.; van Pee, K.
FADH2-dependence of tryptophan 7-halogenase
Adv. Synth. Catal.
347
1163-1167
2005
Pseudomonas fluorescens
-
Yeh, E.; Cole, L.J.; Barr, E.W.; Bollinger, J.M.; Ballou, D.P.; Walsh, C.T.
Flavin redox chemistry precedes substrate chlorination during the reaction of the flavin-dependent halogenase RebH
Biochemistry
45
7904-7912
2006
Lentzea aerocolonigenes
Yeh, E.; Garneau, S.; Walsh, C.T.
Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis
Proc. Natl. Acad. Sci. USA
102
3960-3965
2005
Lentzea aerocolonigenes (Q8KHZ8), Lentzea aerocolonigenes 39243 (Q8KHZ8)
Dong, C.; Flecks, S.; Unversucht, S.; Haupt, C.; van Pee, K.H.; Naismith, J.H.
Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination
Science
309
2216-2219
2005
Pseudomonas fluorescens
Yeh, E.; Blasiak, L.C.; Koglin, A.; Drennan, C.L.; Walsh, C.T.
Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases
Biochemistry
46
1284-1292
2007
Lentzea aerocolonigenes
Hlzer, M.; Burd, W.; Reiig, H.U.; van pee, K.-H.
Substrate specificity and regioselectivity of tryptophan 7-halogenase from Pseudomonas fluorescens BL915
Adv. Synth. Catal.
343
591-595
2001
Pseudomonas fluorescens (Q9RPG3), Pseudomonas fluorescens BL915 (Q9RPG3)
-
Keller, S.; Wage, T.; Hohaus, K.; Hlzer, M.; Eichhorn, E.; van Pee, K.H.
Purification and Partial Characterization of Tryptophan 7-Halogenase (PrnA) from Pseudomonas fluorescens
Angew. Chem. Int. Ed. Engl.
39
2300-2302
2000
Pseudomonas fluorescens
Hammer, P.E.; Hill, D.S.; Lam, S.T.; van Pee, K.H.; Ligon, J.M.
Four genes from Pseudomonas fluorescens that encode the biosynthesis of pyrrolnitrin
Appl. Environ. Microbiol.
63
2147-2154
1997
Pseudomonas fluorescens (P95480)
van Pee, K.H.; Patallo, E.P.
Flavin-dependent halogenases involved in secondary metabolism in bacteria
Appl. Microbiol. Biotechnol.
70
631-641
2006
Lentzea aerocolonigenes (Q8KHZ8), Pseudomonas fluorescens (Q4KAM7)
Kirner, S.; Hammer, P.E.; Hill, D.S.; Altmann, A.; Fischer, I.; Weislo, L.J.; Lanahan, M.; van Pee, K.H.; Ligon, J.M.
Functions encoded by pyrrolnitrin biosynthetic genes from Pseudomonas fluorescens
J. Bacteriol.
180
1939-1943
1998
Pseudomonas fluorescens (P95480)
Bitto, E.; Huang, Y.; Bingman, C.A.; Singh, S.; Thorson, J.S.; Phillips, G.N. Jr.
The structure of flavin-dependent tryptophan 7-halogenase RebH
Proteins
70
289-293
2008
Lentzea aerocolonigenes (Q8KHZ8)
Bitto, E.; Huang, Y.; Bingman, C.A.; Singh, S.; Thorson, J.S.; Phillips, G.N.
The structure of flavin-dependent tryptophan 7-halogenase RebH
Proteins Struct. Funct. Genet.
70
289-293
2008
Lentzea aerocolonigenes (Q8KHZ8)
Lang, A.; Polnick, S.; Nicke, T.; William, P.; Patallo, E.; Naismith, J.; Van Pee, K.
Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis
Angew. Chem. Int. Ed. Engl.
50
2951-2953
2011
Pseudomonas fluorescens
Glenn, W.S.; Nims, E.; OConnor, S.E.
Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor
J. Am. Chem. Soc.
133
19346-19349
2011
Lentzea aerocolonigenes (Q8KHZ8)
Frese, M.; Sewald, N.
Enzymatic halogenation of tryptophan on a gram scale
Angew. Chem. Int. Ed. Engl.
54
298-301
2015
Lentzea aerocolonigenes (Q8KHZ8)
Fraebel, S.; Krischke, M.; Staniek, A.; Warzecha, H.
Recombinant flavin-dependent halogenases are functional in tobacco chloroplasts without co-expression of flavin reductase genes
Biotechnol. J.
11
1586-1594
2016
Lentzea aerocolonigenes (Q8KHZ8)
Frese, M.; Guzowska, P.; Voss, H.; Sewald, N.
Regioselective enzymatic halogenation of substituted tryptophan derivatives using the FAD-dependent halogenase RebH
ChemCatChem
6
1270-1276
2014
Lentzea aerocolonigenes (Q8KHZ8)
-
Heemstra, J.R.Jr.; Walsh, C.T.
Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for Kutzneride assembly
J. Am. Chem. Soc.
130
14024-14025
2008
Kutzneria sp. 744 (A8CF75)
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