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Information on EC 1.14.19.75 - very-long-chain acyl-lipid omega-9 desaturase

for references in articles please use BRENDA:EC1.14.19.75

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IUBMB Comments

The enzyme, characterized from the plant Arabidopsis thaliana, acts on both 24:0 and 26:0 fatty acids, introducing a cis double bond at a position 9 carbons from the methyl end. These very-long-chain fatty acids are found as a minor component of seed lipids, but also in the membrane phosphatidylethanolamine and phosphatidylserine, in sphingolipids, as precursors and components of cuticular and epicuticular waxes, and in suberin.

The expected taxonomic range for this enzyme is: Arabidopsis thaliana
Reaction Schemes
1-hexacosanoyl-2-acyl-[phosphoglycerolipid]
+
2
+
+
2
=
1-[(17Z)-hexacos-17-enoyl]-2-acyl-[phosphoglycerolipid]
+
2
+
2
1-tetracosanoyl-2-acyl-[phosphoglycerolipid]
+
2
+
+
2
=
1-[(15Z)-tetracos-15-enoyl]-2-acyl-[phosphoglycerolipid]
+
2
+
2

Synonyms
atads2, acyl-lipid desaturase2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-hexacosanoyl-2-acyl-[phosphoglycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = 1-[(17Z)-hexacos-17-enoyl]-2-acyl-[phosphoglycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
(1)
-
-
-
1-tetracosanoyl-2-acyl-[phosphoglycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = 1-[(15Z)-tetracos-15-enoyl]-2-acyl-[phosphoglycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
(2)
-
-
-
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