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Information on EC 1.14.15.34 - 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

for references in articles please use BRENDA:EC1.14.15.34
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IUBMB Comments
A cytochrome P-450 (heme-thiolate) protein. Involved in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria.
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The expected taxonomic range for this enzyme is: Streptomyces fradiae
Reaction Schemes
Synonyms
chmH, TylH, tylH1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
20-oxo-5-O-beta-mycaminosyltylactone + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = 5-O-beta-mycaminosyltylonolide + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
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