Disease on EC 1.14.15.3 - alkane 1-monooxygenase
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Acidosis
Effect of dietary acid and calcium on 25-hydroxyvitamin D metabolism by chick kidney.
Adenocarcinoma
Differential Expression of Cytochrome P450 Omega-hydroxylase Isoforms and Their Association with Clinicopathological Features in Pancreatic Ductal Adenocarcinoma.
Albuminuria
Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.
alkane 1-monooxygenase deficiency
Association of a CYP4A11 variant and blood pressure in black men.
alkane 1-monooxygenase deficiency
Genetic variation in CYP4A11 and blood pressure response to mineralocorticoid receptor antagonism or ENaC inhibition: an exploratory pilot study in African Americans.
Ascorbic Acid Deficiency
[Effect of ascorbic acid on 25-hydroxyvitamin D3 metabolism in the kidneys and 1,25-dihydroxyvitamin D3 reception in the small intestine mucosa of guinea pigs]
Asthma
Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.
Bacterial Infections
Altered Inflammatory Responses to Citrobacter rodentium Infection, but not Bacterial Lipopolysaccharide, in Mice Lacking the Cyp4a10 or Cyp4a14 Genes.
Brain Ischemia
Astrocytic cytochrome P450 4A/20-hydroxyeicosatetraenoic acid contributes to angiogenesis in the experimental ischemic stroke.
Breast Neoplasms
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
Carcinogenesis
An evaluation of the human relevance of the liver tumors observed in female mice treated with permethrin based on mode of action.
Carcinoma
Alteration of CYP4A11 expression in renal cell carcinoma: diagnostic and prognostic implications.
Carcinoma
Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
Carcinoma, Hepatocellular
Cytochrome P450 4A11 expression in tumor cells: A favorable prognostic factor for hepatocellular carcinoma patients.
Carcinoma, Hepatocellular
Evaluation of polycyclic aromatic hydrocarbons in the activation of early growth response-1 and peroxisome proliferator activated receptors.
Carcinoma, Hepatocellular
Genistein, Resveratrol, and 5-Aminoimidazole-4-carboxamide-1-{beta}-D-ribofuranoside Induce Cytochrome P450 4F2 Expression through an AMP-Activated Protein Kinase-Dependent Pathway.
Carcinoma, Renal Cell
Alteration of CYP4A11 expression in renal cell carcinoma: diagnostic and prognostic implications.
Cardiomegaly
3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats.
Cardiomegaly
Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart.
Cardiovascular Diseases
Constitutive expression of peroxisome proliferator-activated receptor alpha-regulated genes in dwarf mice.
Cardiovascular Diseases
Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.
Cardiovascular Diseases
Molecular Functionality of Cytochrome P450 4 (CYP4) Genetic Polymorphisms and Their Clinical Implications.
Cerebral Infarction
Haplotype-based case study of human CYP4A11 gene and cerebral infarction in Japanese subject.
Cerebrovascular Disorders
Genetic role of CYP4A11 polymorphisms in the risk of developing cardiovascular and cerebrovascular diseases.
Colitis
Mice Deficient in Cyp4a14 Have An Increased Number of Goblet Cells and Attenuated Dextran Sulfate Sodium-Induced Colitis.
Coronary Artery Disease
A Novel Polymorphism of the CYP4A11 Gene is Associated With Coronary Artery Disease.
Coronary Artery Disease
CYP4A11 polymorphism correlates with coronary endothelial dysfunction in patients with coronary artery disease-The ENCORE Trials.
Coronary Artery Disease
Haplotype study of the CYP4A11 gene and coronary artery disease in Han and Uygur populations in China.
Craniocerebral Trauma
Identification of the miRNA-3185/CYP4A11 axis in cardiac tissue as a biomarker for mechanical asphyxia.
Death, Sudden, Cardiac
Identification of the miRNA-3185/CYP4A11 axis in cardiac tissue as a biomarker for mechanical asphyxia.
Diabetes Mellitus, Type 1
Chronic treatment with Ang-(1-7) reverses abnormal reactivity in the corpus cavernosum and normalizes diabetes-induced changes in the protein levels of ACE, ACE2, ROCK1, ROCK2 and omega-hydroxylase in a rat model of type 1 diabetes.
Diabetes Mellitus, Type 2
Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.
Diabetic Nephropathies
Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy.
Diabetic Nephropathies
SiRNA-Cyp4a14 and diabetic nephropathy: silencing of Cyp4a14 by siRNA inhibits proliferation and fibrosis of mesangial cells.
Dyslipidemias
The role of mercury and cadmium heavy metals in vascular disease, hypertension, coronary heart disease, and myocardial infarction.
Endotoxemia
Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent.
Essential Hypertension
A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men.
Essential Hypertension
Association between the CYP4A11 T8590C variant and essential hypertension: new data from han chinese and a meta-analysis.
Essential Hypertension
Associations of CYP4A11 gene-gene and gene-smoking interactions with essential hypertension in the male eastern Chinese Han population.
Essential Hypertension
CYP4A11 gene T8590C polymorphism is associated with essential hypertension in the male western Chinese Han population.
Essential Hypertension
Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.
Essential Hypertension
The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension.
Fatty Liver
Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.
Fatty Liver
Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice.
Fatty Liver
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.
Fatty Liver
MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement.
Fatty Liver
PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease.
Fatty Liver
The direction of cross affects [corrected] obesity after puberty in male but not female offspring.
Glioma
Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A.
Glioma
Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1.
Glioma
Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma.
Gliosarcoma
9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A.
Glucose Intolerance
The role of mercury and cadmium heavy metals in vascular disease, hypertension, coronary heart disease, and myocardial infarction.
Hemorrhagic Stroke
Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population.
Hepatitis, Chronic
Associations between human liver and kidney cadmium content and immunochemically detected CYP4A11 apoprotein.
Hepatomegaly
Bifonazole, but not the structurally-related clotrimazole, induces both peroxisome proliferation and members of the cytochrome P4504A sub-family in rat liver.
Hepatomegaly
Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.
Hypercalcemia
Parathyroid hormone-related protein (PTHrP) does not regulate 1,25-dihydroxyvitamin D serum levels in hypercalcemia of malignancy.
Hyperglycemia
Pharmacological regulation of cytochrome P450 metabolites of arachidonic acid attenuates cardiac injury in diabetic rats.
Hyperparathyroidism
[Serum concentrations of 1,25-dihydroxyvitamin D in cases of osteomalacia, parathyroid dysfunction and idiopathic hypercalciuria]
Hyperparathyroidism, Primary
Substrate-product relation of 1-hydroxylase activity in primary hyperparathyroidism.
Hypertension
20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR.
Hypertension
A common polymorphism of CYP4A11 is associated with blood pressure in a Chinese population.
Hypertension
A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men.
Hypertension
A polymorphism regulates CYP4A11 transcriptional activity and is associated with hypertension in a Japanese population.
Hypertension
A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure.
Hypertension
Aging Increases Cytochrome P450 4A Modulation of alpha1-Adrenergic Vasoconstriction in Mesenteric Arteries.
Hypertension
Altered Inflammatory Responses to Citrobacter rodentium Infection, but not Bacterial Lipopolysaccharide, in Mice Lacking the Cyp4a10 or Cyp4a14 Genes.
Hypertension
Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.
Hypertension
Altered vitamin D metabolism in the kidney of the spontaneously hypertensive rat.
Hypertension
Arachidonic acid ?-hydroxylase CYP4A11: inter-ethnic variations in the 8590T>C loss-of-function variant.
Hypertension
Arachidonic acid monooxygenase: Genetic and biochemical approaches to physiological/pathophysiological relevance.
Hypertension
Association of a CYP4A11 polymorphism and hypertension in the Mongolian and Han populations of China.
Hypertension
Association of a functional polymorphism in the CYP4A11 gene with systolic blood pressure in survivors of myocardial infarction.
Hypertension
Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy.
Hypertension
Clofibrate prevents the development of hypertension in Dahl salt-sensitive rats.
Hypertension
Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension.
Hypertension
CYP4A11 T8590C polymorphism, salt-sensitive hypertension, and renal blood flow.
Hypertension
Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney.
Hypertension
Differential effect of cytochrome P-450 omega-hydroxylase inhibition on O2-induced constriction of arterioles in SHR with early and established hypertension.
Hypertension
Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid ?-hydroxylation.
Hypertension
Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.
Hypertension
Genetic associations with hypertension: meta-analyses of six candidate genetic variants.
Hypertension
Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.
Hypertension
Genetic role of CYP4A11 polymorphisms in the risk of developing cardiovascular and cerebrovascular diseases.
Hypertension
Genetic variation in CYP4A11 and blood pressure response to mineralocorticoid receptor antagonism or ENaC inhibition: an exploratory pilot study in African Americans.
Hypertension
Hypertension, cardiovascular risk and polymorphisms in genes controlling the cytochrome P450 pathway of arachidonic acid: A sex-specific relation?
Hypertension
Increased Renal Proximal Convoluted Tubule Transport Contributes to Hypertension in Cyp4a14 Knockout Mice.
Hypertension
Lifelong inorganic arsenic compounds consumption affected blood pressure in rats.
Hypertension
Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.
Hypertension
Peroxisome Proliferator Activated Receptor-? Agonist Slows the Progression of Hypertension, Attenuates Plasma Interleukin-6 Levels and Renal Inflammatory Markers in Angiotensin II Infused Mice.
Hypertension
Peroxisome Proliferator-Activated Receptor-? Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension.
Hypertension
Potential for early involvement of CYP isoforms in aspects of human cadmium toxicity.
Hypertension
Regulation of ion transport and blood pressure by cytochrome p450 monooxygenases.
Hypertension
Role of 20-HETE in the antihypertensive effect of transfer of chromosome 5 from Brown Norway to Dahl salt-sensitive rats.
Hypertension
Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat.
Hypertension
Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension.
Hypertension
Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.
Hypertension
T8590C polymorphism of CYP4A11 is a risk factor for hypertension: a meta-analysis.
Hypertension
The Arachidonic Acid Monooxygenase. From Biochemical Curiosity to Physiological/Pathophysiological Significance.
Hypertension
The effect of a single nucleotide polymorphism of the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acid excretion after weight loss.
Hypertension
The role of cytochrome P450 gene rs1126742 polymorphism and risk of hypertension: a systematic review and meta-analysis.
Hypertension
The role of mercury and cadmium heavy metals in vascular disease, hypertension, coronary heart disease, and myocardial infarction.
Hypertension
The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension.
Hypertension
The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure.
Hypertension
Transfer of the CYP4A region of chromosome 5 from Lewis to Dahl S rats attenuates renal injury.
Hypertension
[Altered expressions of alkane monooxygenase and hypoxia inducible factor-1? expression in lung tissue of rat hypoxic pulmonary hypertension].
Hyperthyroidism
Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone.
Hypocalcemia
Effect of vitamin D3 administration on serum 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and osteocalcin in vitamin D-deficient elderly people.
Hypoparathyroidism
[Serum concentrations of 1,25-dihydroxyvitamin D in cases of osteomalacia, parathyroid dysfunction and idiopathic hypercalciuria]
Hypophosphatemia
Hemangiopericytoma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit renal 25-hydroxyvitamin D 1-hydroxylase activity.
Infections
Altered Inflammatory Responses to Citrobacter rodentium Infection, but not Bacterial Lipopolysaccharide, in Mice Lacking the Cyp4a10 or Cyp4a14 Genes.
Infections
Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: Implications for disease-dependent drug-drug interactions.
Infections
Selective role for tumor necrosis factor-?, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen.
Insulin Resistance
Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome p450 and glutathione s-transferase isoforms in a New Zealand obese-derived mouse backcross population.
Insulin Resistance
Effects of daphnetin on lipid metabolism, insulin resistance and oxidative stress in OA?treated HepG2 cells.
Insulin Resistance
Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats.
Ischemic Stroke
Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population.
Ischemic Stroke
Cytochrome 4A11 Genetic Polymorphisms Increase Susceptibility to Ischemic Stroke and Associate with Atherothrombotic Events After Stroke in Chinese.
Ischemic Stroke
Interaction among CYP2C8, EPHX2, and CYP4A11 Gene Variants Significantly Increases the Risk for Ischemic Stroke in Chinese Populations.
Ischemic Stroke
Interactions Among CYP2C8, EPHX2, and CYP4A11 Variants and CYP Plasma Metabolite Levels in Ischemic Stroke.
Liver Cirrhosis
Cytochrome P450 Omega-Hydroxylase 4a14 Attenuates Cholestatic Liver Fibrosis.
Liver Diseases
CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS?induced lipid peroxidation and inflammation.
Liver Diseases
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.
Liver Diseases
Cytochrome P450 Omega-Hydroxylase 4a14 Attenuates Cholestatic Liver Fibrosis.
Liver Diseases
PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease.
Liver Diseases
Translational Implications of the Alcohol-Metabolizing Enzymes, Including Cytochrome P450-2E1, in Alcoholic and Nonalcoholic Liver Disease.
Liver Diseases, Alcoholic
Influence of royal jelly on mouse hepatic gene expression and safety assessment with a DNA microarray.
Liver Neoplasms
Toxicology and carcinogenesis study of chloral hydrate (ad libitum and dietary controlled) (CAS no. 302-17-0) in male B6C3F1 mice (gavage study).
Lung Diseases
Implication of vitamin D-associated factors in patients with non-tuberculous mycobacterial lung disease.
Melanoma
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
Metabolic Diseases
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.
Myocardial Infarction
Association of a functional polymorphism in the CYP4A11 gene with systolic blood pressure in survivors of myocardial infarction.
Myocardial Infarction
Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection.
Myocardial Infarction
Haplotype-based case-control study of CYP4A11 gene and myocardial infarction.
Neoplasm Metastasis
Co-expression network analysis identified six hub genes in association with metastasis risk and prognosis in hepatocellular carcinoma.
Neoplasm Metastasis
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
Neoplasm Metastasis
Cytochrome P450 ?-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer.
Neoplasms
9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A.
Neoplasms
Alteration of CYP4A11 expression in renal cell carcinoma: diagnostic and prognostic implications.
Neoplasms
An evaluation of the human relevance of the liver tumors observed in female mice treated with permethrin based on mode of action.
Neoplasms
Chlorella pyrenoidosa ameliorated L-NAME-induced hypertension and cardiorenal remodeling in rats.
Neoplasms
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
Neoplasms
CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS?induced lipid peroxidation and inflammation.
Neoplasms
Cytochrome P450 4A11 expression in tumor cells: A favorable prognostic factor for hepatocellular carcinoma patients.
Neoplasms
Cytochrome P450 ?-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer.
Neoplasms
Downregulation of CYP2A6 and CYP2C8 in Tumor Tissues Is Linked to Worse Overall Survival and Recurrence-Free Survival from Hepatocellular Carcinoma.
Neoplasms
Hemangiopericytoma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit renal 25-hydroxyvitamin D 1-hydroxylase activity.
Neoplasms
Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma.
Neoplasms
Integrated Proteomics and Bioinformatics to Identify Potential Prognostic Biomarkers in Hepatocellular Carcinoma.
Neoplasms
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
Neoplasms
Parathyroid hormone-related protein (PTHrP) does not regulate 1,25-dihydroxyvitamin D serum levels in hypercalcemia of malignancy.
Neoplasms
Renoprotective effects of soy protein hydrolysates in N(omega)-nitro-L-arginine methyl ester hydrochloride-induced hypertensive rats.
Neoplasms
Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation.
Neoplasms
The Arachidonic Acid Monooxygenase. From Biochemical Curiosity to Physiological/Pathophysiological Significance.
Neoplasms
The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
Neoplasms
Tumor necrosis factor-alpha induces vitamin D-1-hydroxylase activity in normal human alveolar macrophages.
Neoplasms
Urothelial cancer gene regulatory networks inferred from large-scale RNAseq, Bead and Oligo gene expression data.
Non-alcoholic Fatty Liver Disease
Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.
Non-alcoholic Fatty Liver Disease
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS?induced lipid peroxidation and inflammation.
Non-alcoholic Fatty Liver Disease
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.
Non-alcoholic Fatty Liver Disease
Cytochrome P450 Omega-Hydroxylase 4a14 Attenuates Cholestatic Liver Fibrosis.
Non-alcoholic Fatty Liver Disease
Effects of daphnetin on lipid metabolism, insulin resistance and oxidative stress in OA?treated HepG2 cells.
Non-alcoholic Fatty Liver Disease
Influence of royal jelly on mouse hepatic gene expression and safety assessment with a DNA microarray.
Non-alcoholic Fatty Liver Disease
Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model.
Obesity
Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats.
Obesity
Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity.
Obesity
Translational Implications of the Alcohol-Metabolizing Enzymes, Including Cytochrome P450-2E1, in Alcoholic and Nonalcoholic Liver Disease.
Osteomalacia
Hemangiopericytoma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit renal 25-hydroxyvitamin D 1-hydroxylase activity.
Pre-Eclampsia
Arachidonic acid metabolites of CYP4A and CYP4F are altered in women with preeclampsia.
Proteinuria
Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.
Pulmonary Arterial Hypertension
[Altered expressions of alkane monooxygenase and hypoxia inducible factor-1? expression in lung tissue of rat hypoxic pulmonary hypertension].
Renal Insufficiency
Renal 25-hydroxyvitamin D3-1-hydroxylase in patients with renal disease.
Reperfusion Injury
Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection.
Rickets
Normal 24-hydroxylation of vitamin D metabolites in patients with vitamin D-dependency rickets type I. Structural implications for the vitamin D hydroxylases.
Rickets
The effects of 1,25-dihydroxyvitamin D-3 deficiency on Ca(2+)-transport and Ca(2+)-uptake into brush-border membrane vesicles from pig small intestine.
Starvation
Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes.
Stroke
Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population.
Stroke
Astrocytic cytochrome P450 4A/20-hydroxyeicosatetraenoic acid contributes to angiogenesis in the experimental ischemic stroke.
Stroke
Cytochrome 4A11 Genetic Polymorphisms Increase Susceptibility to Ischemic Stroke and Associate with Atherothrombotic Events After Stroke in Chinese.
Stroke
The effect of a single nucleotide polymorphism of the CYP4F2 gene on blood pressure and 20-hydroxyeicosatetraenoic acid excretion after weight loss.
Tuberculosis
Functional analysis of alkane hydroxylases from gram-negative and gram-positive bacteria.
Tuberculosis
The alkane hydroxylase gene of Burkholderia cepacia RR10 is under catabolite repression control.
Uremia
1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis.
Varicose Veins
Cytochromes P450 are differently expressed in normal and varicose human saphenous veins: linkage with varicosis.
Vitamin B 6 Deficiency
[Vitamin D and calcium metabolism in relation to different levels of vitamins B6 and D]
Vitamin D Deficiency
Deficiency of vitamin D metabolites directly stimulates renal 25-hydroxyvitamin D3-1-hydroxylase activity in rats.
Vitamin D Deficiency
Regulation of renal vitamin D hydroxylase activity in vitamin D deficient rats.
Vitamin D Deficiency
Regulation of the ferredoxin component of renal hydroxylases at transcriptional and postranslational levels and of the protein inhibitor of cyclic AMP-dependent kinase.
Vitamin D Deficiency
Vitamin D Deficiency Attenuates Acute Alcohol-Induced Hepatic Lipid Accumulation in Mice.
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