Reference on EC 1.14.15.18 - calcidiol 1-monooxygenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yoon, P.S.; DeLuca, H.F.
Purification and properties of vitamin D hydroxylases
Methods Enzymol.
67
430-440
1980
Gallus gallus
Gray, R.W.; Omdahl, J.L.; Ghazarian, J.G.; DeLuca, H.F.
25-Hydroxycholecalciferol-1-hydroxylase. Subcellular location and properties
J. Biol. Chem.
247
7528-7532
1972
Gallus gallus
Botham, K.M.; Tanaka, Y.; DeLuca, H.F.
25-Hydroxyvitamin D3-1-hydroxylase. Inhibition in vitro by rat and pig tissues
Biochemistry
13
4961-4966
1974
Gallus gallus
Ghazarian, J.G.; Kream, B.; Botham, K.M.; Nickells, M.W.; DeLuca, H.F.
Rat plasma 25-hydroxyvitamin D3 binding protein: an inhibitor of the 25-hydroxyvitamin D3-1alpha-hydroxylase
Arch. Biochem. Biophys.
189
212-220
1978
Gallus gallus
Henry, H.L.; Norman, A.W.
Studies on calciferol metabolism. Regulation of 25-hydroxyvitamin D3-1-hydroxylase in isolated renal mitochondria
Arch. Biochem. Biophys.
172
582-589
1976
Gallus gallus
Botham, K.M.; Ghazarian, J.G.; Kream, B.E.; DeLuca, H.F.
Isolation of an inhibitor of 25-hydroxyvitamin D3-1-hydroxylase from rat serum
Biochemistry
15
2130-2135
1976
Gallus gallus
Paulson, S.K.; DeLuca, H.F.
Subcellular location and properties of rat renal 25-hydroxyvitamin D3-1 alpha-hydroxylase
J. Biol. Chem.
260
11488-11492
1985
Rattus norvegicus
Vieth, R.; Fraser, D.
Kinetic behavior of 25-hydroxyvitamin D-1-hydroxylase and -24-hydroxylase in rat kidney mitochondria
J. Biol. Chem.
254
12455-12460
1979
Rattus norvegicus
Ghazarian, J.G.; Yanda, D.M.
Inhibition of 25-hydroxyvitamin D 1 alpha-hydroxylase by renal mitochondrial protein kinase-catalyzed phosphorylation
Biochem. Biophys. Res. Commun.
132
1095-1102
1985
Gallus gallus
Ghazarian, J.G.; Jefcoate, C.R.; Knutson, J.C.; Orme-Johnson, W.H.; DeLuca, H.F.
Mitochondrial cytochrome P450. A component of chick kidney 25-hydrocholecalciferol-1alpha-hydroxylase
J. Biol. Chem.
249
3026-3033
1974
Gallus gallus
Henry, H.L.; Norman, A.W.
Studies on calciferol metabolism. IX. Renal 25-hydroxy-vitamin D3-1 hydroxylase. Involvement of cytochrome P-450 and other properties
J. Biol. Chem.
249
7529-7535
1974
Gallus gallus
Kulkoski, J.A.; Ghazarian, J.G.
Purification and characterization of the ferredoxin component of 25-hydroxycholecalciferol 1 alpha-hydroxylase
Biochem. J.
177
673-678
1979
Gallus gallus
Gray, R.W.; Ghazarian, J.G.
Solubilization and reconstitution of kidney 25-hydroxyvitamin D3 1 alpha- and 24-hydroxylases from vitamin D-replete pigs
Biochem. J.
259
561-568
1989
Sus scrofa
Pedersen, J.I.; Ghazarian, J.G.; Orme-Johnson, N.R.; DeLuca, H.F.
Isolation of chick renal mitochondrial ferredoxin active in the 25-hydroxyvitamin D3-1alpha-hydroxylase system
J. Biol. Chem.
251
3933-3941
1976
Gallus gallus
Postlind, H.
Separation of the cytochromes P-450 in pig kidney mitochondria catalyzing 1 alpha-, 24- and 26-hydroxylations of 25-hydroxyvitamin D3
Biochem. Biophys. Res. Commun.
168
261-266
1990
Sus scrofa
Hiwatashi, A.; Nishii, Y.; Ichikawa, Y.
Purification of cytochrome P-450D1 alpha (25-hydroxyvitamin D3-1 alpha-hydroxylase) of bovine kidney mitochondria
Biochem. Biophys. Res. Commun.
105
320-327
1982
Bos taurus
Hagenfeldt, Y.; Pedersen, J.I.; Bjrkhem, I.
Properties of guinea-pig kidney 25-hydroxyvitamin D3 1 alpha-hydroxylase assayed by isotope dilution-mass spectrometry
Biochem. J.
250
521-526
1988
Cavia porcellus
Paulson, S.K.; Phelps, M.; DeLuca, H.F.
Assay and properties of rat yolk sac 25-hydroxyvitamin D3 1 alpha-hydroxylase
Biochemistry
25
6821-6826
1986
Rattus norvegicus
Lobaugh, B.; Almond, J.R.; Drezner, M.K.
Measurement of 25-hydroxyvitamin D 1-alpha-hydroxylase activity in mammalian kidney
Methods Enzymol.
123
159-167
1986
Mammalia
Delvin, E.E.; Arabian, A.
Kinetics and regulation of 25-hydroxycholecalciferol 1 alpha-hydroxylase from cells isolated from human term decidua
Eur. J. Biochem.
163
659-662
1987
Homo sapiens
Burgos-Trinidad, M.; Ismail, R.; Ettinger, R.A.; Prahl, J.M.; DeLuca, H.F.
Immunopurified 25-hydroxyvitamin D 1a-hydroxylase and 1,25-dihydroxyvitamin D 24-hydroxylase are closely related but distinct enzymes
J. Biol. Chem.
267
3498-3505
1992
Gallus gallus
Grieff, M.; Dusso, A.; Mori, T.; Nishii, Y.; Slatopolsky, E.; Brown, A.J.
22-Oxacalcitriol suppresses 25-hydroxycholecalciferol-1a-hydroxylase in rat kidney
Biochem. Biophys. Res. Commun.
185
191-196
1992
Rattus norvegicus
Daniel, D.; Middleton, R.; Henry, H.L.; Okamura, W.H.
Inhibitors of 25-hydroxyvitamin D3 1a-hydroxylase: A-ring oxa analogs of 25-hydroxyvitamin D3
J. Org. Chem.
61
5617-5625
1996
Gallus gallus
-
Nakamura, Y.; Eto, T.A.; Taniguchi, T.; Miyamoto, K.; Nagatomo, J.; Shiotsuki, H.; Sueta, H.; Higashi, S.; Okuda, K.I.; Setoguchi, T.
Purification and characterization of 25-hydroxyvitamin D3 1alpha-hydroxylase from rat kidney mitochondria
FEBS Lett.
419
45-48
1997
Rattus norvegicus
Takeyama, K.i.; Kitanaka, S.; Sato, T.; Kobori, M.; Yanagisawa, J.; Kato, S.
25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis
Science
277
1827-1830
1997
Mus musculus (O35084)
Sawada, N.; Sakaki, T.; Kitanaka, S.; Takeyama, K.i.; Kato, S.; Inouye, K.
Enzymatic properties of human 25-hydroxyvitamin D3 1alpha-hydroxylase: coexpression with adrenodoxin and NADPH-adrenodoxin reductase in Escherichia coli
Eur. J. Biochem.
265
950-956
1999
Homo sapiens
Sakaki, T.; Sawada, N.; Takeyama, K.i.; Kato, S.; Inouye, K.
Enzymic properties of mouse 25-hydroxyvitamin D3 1alpha-hydroxylase expressed in Escherichia coli
Eur. J. Biochem.
259
731-738
1999
Mus musculus
Yoshida, T.; Yoshida, N.; Nakamura, A.; Monkawa, T.; Hayashi, M.; Saruta, T.
Cloning of porcine 25-hydroxyvitamin D3 1alpha-hydroxylase and its regulation by cAMP in LLC-PK1 cells
J. Am. Soc. Nephrol.
10
963-970
1999
Sus scrofa (Q9XS57), Sus scrofa
Hagenfeldt, Y.; Berlin, T.
The human renal 25-hydroxyvitamin D3-1a-hydroxylase: properties studied by isotope-dilution mass spectrometry
Eur. J. Clin. Invest.
22
223-228
1992
Homo sapiens
Bareis, P.; Kallay, E.; Bischof, M.G.; Bises, G.; Hofer, H.; Potzi, C.; Manhardt, T.; Bland, R.; Cross, H.S.
Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3)
Exp. Cell Res.
276
320-327
2002
Homo sapiens
Inouye, K.; Sakaki, T.
Enzymatic studies on the key enzymes of vitamin D metabolism; 1alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24)
Biotechnol. Annu. Rev.
7
179-194
2001
Homo sapiens, Mus musculus
Diaz, L.; Arranz, C.; Avila, E.; Halhali, A.; Vilchis, F.; Larrea, F.
Expression and activity of 25-hydroxyvitamin D-1alpha-hydroxylase are restricted in cultures of human syncytiotrophoblast cells from preeclamptic pregnancies
J. Clin. Endocrinol. Metab.
87
3876-3882
2002
Homo sapiens
Hosseinpour, F.; Norlin, M.; Wikvall, K.
Kidney microsomal 25- and 1alpha-hydroxylase in vitamin D metabolism: catalytic properties, molecular cloning, cellular localization and expression during development
Biochim. Biophys. Acta
1580
133-144
2002
Sus scrofa
Somjen, D.; Weisman, Y.; Kohen, F.; Gayer, B.; Limor, R.; Sharon, O.; Jaccard, N.; Knoll, E.; Stern, N.
25-Hydroxyvitamin D3-1alpha-hydroxylase is expressed in human vascular smooth muscle cells and is upregulated by parathyroid hormone and estrogenic compounds
Circulation
111
1666-1671
2005
Homo sapiens
Panda, D.K.; Miao, D.; Bolivar, I.; Li, J.; Huo, R.; Hendy, G.N.; Goltzman, D.
Inactivation of the 25-hydroxyvitamin D 1alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis
J. Biol. Chem.
279
16754-16766
2004
Mus musculus
St-Arnaud, R.; Dardenne, O.; Prud'homme, J.; Hacking, S.A.; Glorieux, F.H.
Conventional and tissue-specific inactivation of the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1)
J. Cell. Biochem.
88
245-251
2003
Mus musculus
Eyles, D.W.; Smith, S.; Kinobe, R.; Hewison, M.; McGrath, J.J.
Distribution of the vitamin D receptor and 1alpha-hydroxylase in human brain
J. Chem. Neuroanat.
29
21-30
2005
Homo sapiens
Diesel, B.; Seifert, M.; Radermacher, J.; Fischer, U.; Tilgen, W.; Reichrath, J.; Meese, E.
Towards a complete picture of splice variants of the gene for 25-hydroxyvitamin D3 1alpha-hydroxylase in brain and skin cancer
J. Steroid Biochem. Mol. Biol.
89-90
527-532
2004
Homo sapiens
Khorchide, M.; Lechner, D.; Cross, H.S.
Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells
J. Steroid Biochem. Mol. Biol.
93
167-172
2005
Homo sapiens
Ma, J.F.; Nonn, L.; Campbell, M.J.; Hewison, M.; Feldman, D.; Peehl, D.M.
Mechanisms of decreased Vitamin D 1alpha-hydroxylase activity in prostate cancer cells
Mol. Cell. Endocrinol.
221
67-74
2004
Homo sapiens
Friedrich, M.; Diesing, D.; Cordes, T.; Fischer, D.; Becker, S.; Chen, T.C.; Flanagan, J.N.; Tangpricha, V.; Gherson, I.; Holick, M.F.; Reichrath, J.
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue
Anticancer Res.
26
2615-2620
2006
Homo sapiens
Furster, C.; Bergman, T.; Wikvall, K.
Biochemical characterization of a truncated form of CYP27A purified from rabbit liver mitochondria
Biochem. Biophys. Res. Commun.
263
663-666
1999
Oryctolagus cuniculus
Segersten, U.; Holm, P.K.; Bjrklund, P.; Hessman, O.; Nordgren, H.; Binderup, L.; Akerstrm, G.; Hellman, P.; Westin, G.
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue
Breast Cancer Res.
7
R980-R986
2005
Homo sapiens (O15528)
Matusiak, D.; Murillo, G.; Carroll, R.E.; Mehta, R.G.; Benya, R.V.
Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon
Cancer Epidemiol. Biomarkers Prev.
14
2370-2376
2005
Homo sapiens
Kallay, E.; Bises, G.; Bajna, E.; Bieglmayer, C.; Gerdenitsch, W.; Steffan, I.; Kato, S.; Armbrecht, H.J.; Cross, H.S.
Colon-specific regulation of vitamin D hydroxylases - a possible approach for tumor prevention
Carcinogenesis
26
1581-1589
2005
Homo sapiens
Yamamoto, K.; Uchida, E.; Urushino, N.; Sakaki, T.; Kagawa, N.; Sawada, N.; Kamakura, M.; Kato, S.; Inouye, K.; Yamada, S.
Identification of the amino acid residue of CYP27B1 responsible for binding of 25-hydroxyvitamin D3 whose mutation causes vitamin D-dependent rickets type 1
J. Biol. Chem.
280
30511-30516
2005
Mus musculus
Xue, Y.; Zhang, Z.; Karaplis, A.C.; Hendy, G.N.; Goltzman, D.; Miao, D.
Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1alpha-hydroxylase and PTH double knockout mice
J. Bone Miner. Res.
20
1766-1777
2005
Mus musculus
Stoffels, K.; Overbergh, L.; Giulietti, A.; Verlinden, L.; Bouillon, R.; Mathieu, C.
Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes
J. Bone Miner. Res.
21
37-47
2006
Homo sapiens
Overbergh, L.; Stoffels, K.; Waer, M.; Verstuyf, A.; Bouillon, R.; Mathieu, C.
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction
J. Clin. Endocrinol. Metab.
91
3566-3574
2006
Homo sapiens (O15528), Homo sapiens
Khadzkou, K.; Buchwald, P.; Westin, G.; Dralle, H.; Akerstroem, G.; Hellman, P.
25-hydroxyvitamin D3 1alpha-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma
J. Histochem. Cytochem.
54
355-361
2006
Homo sapiens
Hendrix, I.; Anderson, P.H.; Omdahl, J.L.; May, B.K.; Morris, H.A.
Response of the 5-flanking region of the human 25-hydroxyvitamin D 1alpha-hydroxylase gene to physiological stimuli using a transgenic mouse model
J. Mol. Endocrinol.
34
237-245
2005
Homo sapiens
Carneiro de Lyra, E.; Amorim da Silva, I.; Katayama, M.L.; Brentani, M.M.; Nonogaki, S.; Goes, J.C.; Folgueira, M.A.
25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer
J. Steroid Biochem. Mol. Biol.
100
184-192
2006
Homo sapiens
Townsend, K.; Evans, K.N.; Campbell, M.J.; Colston, K.W.; Adams, J.S.; Hewison, M.
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment
J. Steroid Biochem. Mol. Biol.
97
103-109
2005
Homo sapiens
Schroeder, O.; Turak, S.; Daniel, C.; Gaschott, T.; Stein, J.
Upregulation of 25-hydroxyvitamin D3-1alpha-hydroxylase by butyrate in Caco-2 cells
World J. Gastroenterol.
11
7136-7141
2005
Homo sapiens
Wang, L.; Persons, K.S.; Jamieson, D.; Flanagan, J.N.; Hsu, H.H.; Holick, M.F.; Luo, Z.; Sakaki, T.; Urushino, N.; Faller, D.V.; Chen, T.C.
Prostate 25-hydroxyvitamin D-1alpha-hydroxylase is up-regulated by suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor
Anticancer Res.
28
2009-2013
2008
Homo sapiens
Chen, T.C.
25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate
Anticancer Res.
28
2015-2017
2008
Homo sapiens
Bajwa, A.; Forster, M.N.; Maiti, A.; Woolbright, B.L.; Beckman, M.J.
Specific regulation of CYP27B1 and VDR in proximal versus distal renal cells
Arch. Biochem. Biophys.
477
33-42
2008
Mus musculus
Fischer, D.; Seifert, M.; Becker, S.; Ludders, D.; Cordes, T.; Reichrath, J.; Friedrich, M.
25-Hydroxyvitamin D3 1alpha-hydroxylase splice variants in breast cell lines MCF-7 and MCF-10
Cancer Genomics Proteomics
4
295-300
2007
Homo sapiens
Urushino, N.; Nakabayashi, S.; Arai, M.A.; Kittaka, A.; Chen, T.C.; Yamamoto, K.; Hayashi, K.; Kato, S.; Ohta, M.; Kamakura, M.; Ikushiro, S.; Sakaki, T.
Kinetic studies of 25-hydroxy-19-nor-vitamin D3 and 1alpha,25-dihydroxy-19-nor-vitamin D3 hydroxylation by CYP27B1 and CYP24A1
Drug Metab. Dispos.
35
1482-1488
2007
Mus musculus
Wu, S.; Ren, S.; Nguyen, L.; Adams, J.S.; Hewison, M.
Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production
Endocrinology
148
3410-3418
2007
Homo sapiens
Hewison, M.; Burke, F.; Evans, K.N.; Lammas, D.A.; Sansom, D.M.; Liu, P.; Modlin, R.L.; Adams, J.S.
Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease
J. Steroid Biochem. Mol. Biol.
103
316-321
2007
Homo sapiens
Armbrecht, H.J.; Boltz, M.A.; Ritter, C.S.; Brown, A.J.
Parathyroid hormone stimulation of the renal 25-hydroxyvitamin D-1alpha-hydroxylase-effect of age and free radicals
J. Steroid Biochem. Mol. Biol.
103
330-333
2007
Sus scrofa
Somjen, D.; Katzburg, S.; Stern, N.; Kohen, F.; Sharon, O.; Limor, R.; Jaccard, N.; Hendel, D.; Weisman, Y.
25 hydroxy-vitamin D(3)-1alpha hydroxylase expression and activity in cultured human osteoblasts and their modulation by parathyroid hormone, estrogenic compounds and dihydrotestosterone
J. Steroid Biochem. Mol. Biol.
107
238-244
2007
Homo sapiens
Yasutake, Y.; Fujii, Y.; Cheon, W.K.; Arisawa, A.; Tamura, T.
Crystallization and preliminary X-ray diffraction studies of vitamin D3 hydroxylase, a novel cytochrome P450 isolated from Pseudonocardia autotrophica
Acta Crystallogr. Sect. F
65
372-375
2009
Pseudonocardia autotrophica
McCarthy, K.; Laban, C.; Bustin, S.A.; Ogunkolade, W.; Khalaf, S.; Carpenter, R.; Jenkins, P.J.
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue
Anticancer Res.
29
155-157
2009
Homo sapiens
Fischer, D.; Thome, M.; Becker, S.; Cordes, T.; Diedrich, K.; Friedrich, M.; Thill, M.
25-Hydroxyvitamin D3 1alpha-hydroxylase splice variants in benign and malignant ovarian cell lines and tissue
Anticancer Res.
29
3627-3633
2009
Homo sapiens
Fischer, D.; Becker, S.; Cordes, T.; Buecker, B.; Diedrich, K.; Friedrich, M.; Salehin, D.; Thill, M.
Vitamin D-24-hydroxylase in benign and malignant breast tissue and cell lines
Anticancer Res.
29
3641-3645
2009
Homo sapiens
Seifert, M.; Tilgen, W.; Reichrath, J.
Expression of 25-hydroxyvitamin D-1alpha-hydroxylase (1alphaOHase, CYP27B1) splice variants in HaCaT keratinocytes and other skin cells: modulation by culture conditions and UV-B treatment in vitro
Anticancer Res.
29
3659-3667
2009
Homo sapiens
Cross, H.S.; Nittke, T.; Peterlik, M.
Modulation of vitamin D synthesis and catabolism in colorectal mucosa: a new target for cancer prevention
Anticancer Res.
29
3705-3712
2009
Homo sapiens
Farooque, A.; Moss, C.; Zehnder, D.; Hewison, M.; Shaw, N.J.
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis
Br. J. Dermatol.
160
423-425
2009
Homo sapiens
Zhong, Y.; Armbrecht, H.J.; Christakos, S.
Calcitonin, a regulator of the 25-hydroxyvitamin D3 1alpha-hydroxylase gene
J. Biol. Chem.
284
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2009
Sus scrofa
Novakovic, B.; Sibson, M.; Ng, H.K.; Manuelpillai, U.; Rakyan, V.; Down, T.; Beck, S.; Fournier, T.; Evain-Brion, D.; Dimitriadis, E.; Craig, J.M.; Morley, R.; Saffery, R.
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface
J. Biol. Chem.
284
14838-14848
2009
Homo sapiens
Lauter, K.; Arnold, A.
Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism
J. Bone Miner. Res.
24
102-104
2009
Homo sapiens
St-Arnaud, R.; Arabian, A.; Yu, V.W.; Akhouayri, O.; Knutson, J.C.; Strugnell, S.A.
1alpha,24(S)(OH)2D2 normalizes bone morphology and serum parathyroid hormone without hypercalcemia in 25-hydroxyvitamin D-1-hydroxylase (CYP27B1)-deficient mice, an animal model of vitamin D deficiency with secondary hyperparathyroidism
J. Endocrinol. Invest.
31
711-717
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Mus musculus
Bevelander, G.S.; Pinto, E.S.; Canario, A.V.; Spanings, T.; Flik, G.
CYP27A1 expression in gilthead sea bream (Sparus auratus, L.): effects of calcitriol and parathyroid hormone-related protein
J. Endocrinol.
196
625-635
2008
Sparus aurata (B0BCH8)
Li, J.; Byrne, M.E.; Chang, E.; Jiang, Y.; Donkin, S.S.; Buhman, K.K.; Burgess, J.R.; Teegarden, D.
1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes
J. Steroid Biochem. Mol. Biol.
112
122-126
2008
Rattus norvegicus
Ohnishi, M.; Nakatani, T.; Lanske, B.; Razzaque, M.S.
Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase
Kidney Int.
75
1166-1172
2009
Mus musculus
Yasutake, Y.; Fujii, Y.; Nishioka, T.; Cheon, W.K.; Arisawa, A.; Tamura, T.
Structural evidence for enhancement of sequential vitamin D3 hydroxylation activities by directed evolution of cytochrome P450 vitamin D3 hydroxylase
J. Biol. Chem.
285
31193-31201
2010
Pseudonocardia autotrophica
Dhawan, P.; Christakos, S.
Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the vitamin D receptor in 24(OH)ase transcription
J. Cell. Biochem.
110
1314-1323
2010
Homo sapiens
Tang, E.K.; Voo, K.J.; Nguyen, M.N.; Tuckey, R.C.
Metabolism of substrates incorporated into phospholipid vesicles by mouse 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1)
J. Steroid Biochem. Mol. Biol.
119
171-179
2010
Mus musculus
Lagishetty, V.; Chun, R.F.; Liu, N.Q.; Lisse, T.S.; Adams, J.S.; Hewison, M.
1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines
J. Steroid Biochem. Mol. Biol.
121
228-233
2010
Homo sapiens
Urbschat, A.; Paulus, P.; von Quernheim, Q.F.; Brueck, P.; Badenhoop, K.; Zeuzem, S.; Ramos-Lopez, E.
Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma
Eur. J. Clin. Invest.
43
1282-1290
2013
Homo sapiens
Ritter, C.S.; Haughey, B.H.; Armbrecht, H.J.; Brown, A.J.
Distribution and regulation of the 25-hydroxyvitamin D3 1alpha-hydroxylase in human parathyroid glands
J. Steroid Biochem. Mol. Biol.
130
73-80
2012
Homo sapiens
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