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Information on EC 1.14.14.9 - 4-hydroxyphenylacetate 3-monooxygenase

for references in articles please use BRENDA:EC1.14.14.9
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IUBMB Comments
The enzyme from Escherichia coli attacks a broad spectrum of phenolic compounds. The enzyme uses FADH2 as a substrate rather than a cofactor . FADH2 is provided by EC 1.5.1.36, flavin reductase (NADH) [5,6].
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The enzyme appears in viruses and cellular organisms
Synonyms
4 HPA 3-hydroxyylase, 4-HPA hydroxylase, 4-hydroxyphenylacetate 3-hydroxylase, 4-hydroxyphenylacetic acid 3-hydroxylase, 4HPA 3-monooxygenase, 4HPA3H, C2-hpah, EC 1.14.13.3, HPA 3-hydroxylase, HpaB, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O
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