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Information on EC 1.14.14.89 - 4'-methoxyisoflavone 2'-hydroxylase

for references in articles please use BRENDA:EC1.14.14.89

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IUBMB Comments

A cytochrome P-450 (heme-thiolate) protein. Acts on isoflavones with a 4'-methoxy group, such as formononetin and biochanin A. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. EC 1.14.14.90, isoflavone 2'-hydroxylase, is less specific and acts on other isoflavones as well as 4'-methoxyisoflavones.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
daidzein and genistein reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
formononetin + [reduced NADPH-hemoprotein reductase] + O2 = 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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