Any feedback?
Please rate this page

BRENDA support

show all | hide all No of entries

Information on EC - flavanoid 3',5'-hydroxylase

for references in articles please use BRENDA:EC1.14.14.81
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
A cytochrome P-450 (heme-thiolate) protein found in plants. The 3',5'-dihydroxyflavanone is formed via the 3'-hydroxyflavanone. In Petunia hybrida the enzyme acts on naringenin, eriodictyol, dihydroquercetin (taxifolin) and dihydrokaempferol (aromadendrin). The enzyme catalyses the hydroxylation of 5,7,4'-trihydroxyflavanone (naringenin) at either the 3' position to form eriodictyol or at both the 3' and 5' positions to form 5,7,3',4',5'-pentahydroxyflavanone (dihydrotricetin). The enzyme also catalyses the hydroxylation of 3,5,7,3',4'-pentahydroxyflavanone (taxifolin) at the 5' position, forming ampelopsin.
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The enzyme appears in viruses and cellular organisms
f3'5'h, flavonoid 3',5'-hydroxylase, flavonoid 3'5'-hydroxylase, flavonoid 3'5' hydroxylase, cyp75a, cyp75a31, f3',5'h, more
a 3'-hydroxyflavanone + [reduced NADPH-hemoprotein reductase] + O2 = a 3',5'-dihydroxyflavanone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
a flavanone + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = a 3',5'-dihydroxyflavanone + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
overall reaction
a flavanone + [reduced NADPH-hemoprotein reductase] + O2 = a 3'-hydroxyflavanone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram