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Information on EC 1.14.14.141 - psoralen synthase

for references in articles please use BRENDA:EC1.14.14.141
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IUBMB Comments
This microsomal cytochrome P-450-dependent enzyme is specific for (+)-marmesin, and to a much lesser extent 5-hydroxymarmesin, as substrate. Furanocoumarins protect plants from fungal invasion and herbivore attack. (+)-Columbianetin, the angular furanocoumarin analogue of the linear furanocoumarin (+)-marmesin, is not a substrate for the enzyme but it is a competitive inhibitor.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
cyp71aj3, cyp71aj1, cyp71aj2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+)-marmesin + [reduced NADPH-hemoprotein reductase] + O2 = psoralen + [oxidized NADPH-hemoprotein reductase] + acetone + 2 H2O
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PATHWAY SOURCE
PATHWAYS
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