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Information on EC 1.14.13.235 - indole-3-acetate monooxygenase

for references in articles please use BRENDA:EC1.14.13.235

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IUBMB Comments

The enzyme, characterized from Pseudomonas putida strains, catalyses the first step in a pathway for degradation of the plant hormone indole-3-acetate. When acting on indole, the enzyme forms indoxyl, which reacts spontaneously with oxygen to form the blue dye indigo.

The enzyme appears in viruses and cellular organisms

Synonyms
iacA, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(indol-3-yl)acetate + NADH + H+ + O2 = (2-hydroxy-1H-indol-3-yl)acetate + NAD+ + H2O
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
indole-3-acetate degradation I, indole-3-acetate degradation II
Highest Expressing Human Cell Lines
Cell Line Links Gene Links