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Information on EC 1.14.13.159 - vitamin D 25-hydroxylase

for references in articles please use BRENDA:EC1.14.13.159

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transferred to EC 1.14.14.24
IUBMB Comments

A microsomal enzyme isolated from human and mouse liver which bioactivates vitamin D3. While multiple isoforms (CYP27A1, CYP2J2/3, CYP3A4, CYP2D25 and CYP2C11) are able to catalyse the reaction in vitro, only CYP2R1 is thought to catalyse the reaction in humans in vivo .

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