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Information on EC 1.14.13.128 - 7-methylxanthine demethylase

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IUBMB Comments
A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida prefers NADH over NADPH. The enzyme is specific for 7-methylxanthine . Forms part of the caffeine degradation pathway.
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The enzyme appears in viruses and cellular organisms
Synonyms
7-methylxanthine-specific N-demethylase, caffeine demethylase, heteroxanthine demethylase, methylxanthine N-demethylase, N-demethylase, ndmA, NdmC, theobromine demethylase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
7-methylxanthine + O2 + NAD(P)H + H+ = xanthine + NAD(P)+ + H2O + formaldehyde
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