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Information on EC 1.14.12.19 - 3-phenylpropanoate dioxygenase

for references in articles please use BRENDA:EC1.14.12.19

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IUBMB Comments

This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation. It catalyses the insertion of both atoms of molecular oxygen into positions 2 and 3 of the phenyl ring of 3-phenylpropanoate or (2E)-3-phenylprop-2-enoate.

The expected taxonomic range for this enzyme is: Bacteria, Archaea

Synonyms
3-phenylpropionate dioxygenase, hcaa1a2cd, hca dioxygenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E)-3-phenylprop-2-enoate + NADH + H+ + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NAD+
show the reaction diagram
(2)
-
-
-
3-phenylpropanoate + NADH + H+ + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
3-phenylpropanoate and 3-(3-hydroxyphenyl)propanoate degradation to 2-hydroxypentadienoate, cinnamate and 3-hydroxycinnamate degradation to 2-hydroxypentadienoate
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