Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2,4-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + NAD+ + Cl- + CO2
2,6-dichlorobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: 19% of the activity with 2-chlorobenzoate
Products: -
?
2-amino-4-chlorobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: 28% of the activity with 2-chlorobenzoate
Products: -
?
2-amino-5-chlorobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: 27% of the activity with 2-chlorobenzoate
Products: -
?
2-aminobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: -
Products: -
?
2-bromobenzoate + NADH + O2
catechol + bromide + NAD+ + CO2
2-chloro-5-bromobenzoate + NADH + O2
4-bromocatechol + chloride + NAD+ + CO2
-
Substrates: 50% of the activity with 2-chlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
3-chlorocatechol + NAD+ + CO2
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
2-fluorobenzoate + NADH + O2
catechol + fluoride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-hydroxybenzoate + NADH + O2
catechol + ? + NAD+ + CO2
-
Substrates: -
Products: -
?
2-iodobenzoate + NADH + O2
catechol + iodide + NAD+ + CO2
2-methoxybenzoate + NADH + O2
catechol + ? + NAD+ + CO2
-
Substrates: -
Products: -
?
2-methylbenzoate + NADH + O2
o-cresol + ? + NAD+ + CO2
3,4-dichlorobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: 10% of the activity with 2-chlorobenzoate
Products: -
?
3,5-dichlorobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: 16% of the activity with 2-chlorobenzoate
Products: -
?
3-chlorobenzoate + NADH + H+ + O2
3-chlorocatechol + NAD+ + CO2
-
Substrates: -
Products: -
?
3-chlorobenzoate + NADH + H+ + O2
4-chlorocatechol + NAD+ + CO2
3-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: 15% of the activity with 2-chlorobenzoate
Products: -
?
3-chlorobenzoate + NADH + O2
? + NAD+ + CO2
-
Substrates: -
Products: -
?
4-amino-2-chlorobenzoate + NADH + O2
4-aminocatechol + chloride + NAD+ + CO2
-
Substrates: 21% of the activity with 2-chlorobenzoate
Products: -
?
4-chlorobenzoate + NADH + H+ + O2
4-chlorocatechol + NAD+ + CO2
-
Substrates: -
Products: -
?
4-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: 21% of the activity with 2-chlorobenzoate
Products: -
?
anthranilate + NADH + O2
catechol + ? + NAD+ + CO2
-
Substrates: -
Products: -
?
benzoate + NADH + H+ + O2
3,5-cyclohexadiene-1,2-diol + NAD+ + CO2
-
Substrates: 37% of the activity with 2-chlorobenzoate
Products: -
?
benzoate + NADH + H+ + O2
catechol + NAD+ + CO2
additional information
?
-
2,4-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
-
Substrates: 50% of the activity with 2-chlorobenzoate
Products: -
?
2,4-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
-
Substrates: 50% of the activity with 2-chlorobenzoate
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
-
Substrates: 38% of the activity with 2-chlorobenzoate
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
-
Substrates: 38% of the activity with 2-chlorobenzoate
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + NAD+ + Cl- + CO2
-
Substrates: involved in the metabolism of 2,5-dichlorobenzoate
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + NAD+ + Cl- + CO2
-
Substrates: involved in the metabolism of 2,5-dichlorobenzoate
Products: -
?
2-bromobenzoate + NADH + O2
catechol + bromide + NAD+ + CO2
-
Substrates: -
Products: -
?
2-bromobenzoate + NADH + O2
catechol + bromide + NAD+ + CO2
-
Substrates: -
Products: -
?
2-bromobenzoate + NADH + O2
catechol + bromide + NAD+ + CO2
-
Substrates: 107% of the activity with 2-chlorobenzoate
Products: -
?
2-bromobenzoate + NADH + O2
catechol + bromide + NAD+ + CO2
-
Substrates: 107% of the activity with 2-chlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
3-chlorocatechol + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
3-chlorocatechol + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: the oxygen in the enzymatically catechol is derived from molecular oxygen, the formed byproduct 2,3-dihydroxybenzoate is suggested to be a dead end metabolite
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: initial step in the degradation of aromatic compounds
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: first step of 2-chlorobenzoate degradation via meta-cleavage
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: no growth on 2-chlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: no growth on 2-chlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: involved in the metabolism of 2-chlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: involved in the metabolism of 2-chlorobenzoate
Products: -
?
2-iodobenzoate + NADH + O2
catechol + iodide + NAD+ + CO2
-
Substrates: -
Products: -
?
2-iodobenzoate + NADH + O2
catechol + iodide + NAD+ + CO2
-
Substrates: -
Products: -
?
2-iodobenzoate + NADH + O2
catechol + iodide + NAD+ + CO2
-
Substrates: 130% of the activity with 2-chlorobenzoate
Products: -
?
2-iodobenzoate + NADH + O2
catechol + iodide + NAD+ + CO2
-
Substrates: 130% of the activity with 2-chlorobenzoate
Products: -
?
2-methylbenzoate + NADH + O2
o-cresol + ? + NAD+ + CO2
-
Substrates: -
Products: -
?
2-methylbenzoate + NADH + O2
o-cresol + ? + NAD+ + CO2
-
Substrates: named o-toluate
Products: -
?
3-chlorobenzoate + NADH + H+ + O2
4-chlorocatechol + NAD+ + CO2
-
Substrates: -
Products: -
?
3-chlorobenzoate + NADH + H+ + O2
4-chlorocatechol + NAD+ + CO2
-
Substrates: -
Products: -
?
benzoate + NADH + H+ + O2
catechol + NAD+ + CO2
-
Substrates: -
Products: -
?
benzoate + NADH + H+ + O2
catechol + NAD+ + CO2
-
Substrates: -
Products: -
?
benzoate + NADH + H+ + O2
catechol + NAD+ + CO2
-
Substrates: 2-chloro-3,5-cyclohexadiene-1,2-diol-1-carboxylic acid as unstable intermediate
Products: -
?
benzoate + NADH + H+ + O2
catechol + NAD+ + CO2
-
Substrates: 2-chloro-3,5-cyclohexadiene-1,2-diol-1-carboxylic acid as unstable intermediate
Products: -
?
additional information
?
-
-
Substrates: very broad substrate specificity
Products: -
?
additional information
?
-
-
Substrates: very broad substrate specificity is listed, benzoate analogs with substituents in ortho position are preferred. Trichloroethylene, dihydroxybenzoates, benzene chlorobenzene, toluene, phenol and chlorophenylacetate isomers do not serve as substrates
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + NAD+ + Cl- + CO2
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + NAD+ + Cl- + CO2
-
Substrates: involved in the metabolism of 2,5-dichlorobenzoate
Products: -
?
2,5-dichlorobenzoate + NADH + O2
4-chlorocatechol + NAD+ + Cl- + CO2
-
Substrates: involved in the metabolism of 2,5-dichlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: initial step in the degradation of aromatic compounds
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: first step of 2-chlorobenzoate degradation via meta-cleavage
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: involved in the metabolism of 2-chlorobenzoate
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: -
Products: -
?
2-chlorobenzoate + NADH + H+ + O2
catechol + chloride + NAD+ + CO2
-
Substrates: involved in the metabolism of 2-chlorobenzoate
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Fetzner, S.; Muller, R.; Lingens, F.
Degradation of 2-chlorobenzoate by Pseudomonas cepacia 2CBS
Biol. Chem. Hoppe-Seyler
370
1173 - 1182
1989
Burkholderia cepacia
brenda
Fetzner, S.; Muller, R.; Lingens, F.
Purification and some properties of 2-halobenzoate 1,2-dioxygenase, a two-component enzyme system from Pseudomonas cepacia 2CBS
J. Bacteriol.
174
279-290
1992
Burkholderia cepacia
brenda
Haak, B.; Fetzner, S.; Lingens, F.
Cloning, nucleotide sequence, and expression of the plasmid-encoded genes for the two-component 2-halobenzoate 1,2-dioxygenase from Pseudomonas cepacia 2CBS
J. Bacteriol.
177
667-675
1995
Burkholderia cepacia
brenda
Riedel, A.; Fetzner, S.; Rampp, M.; Lingens, F.; Liebl, U.; Zimmermann, J.L.; Nitschke, W.
EPR, electron spin echo envelope modulation, and electron nuclear double resonance studies of the 2Fe2S centers of the 2-halobenzoate 1,2-dioxygenase from Burkholderia (Pseudomonas) cepacia 2CBS
J. Biol. Chem.
270
30869-30873
1995
Burkholderia cepacia
brenda
Fava, F.; Baldoni, F.; Marchetti, L.
2-Chlorobenzoic acid and 2,5-dichlorobenzoic acid metabolism by crude extracts of Pseudomonas sp. CPE2 strain
Lett. Appl. Microbiol.
22
275-279
1996
Pseudomonas sp., Pseudomonas sp. CPE2
brenda
Suzuki, K.; Ogawa, N.; Miyashita, K.
Expression of 2-halobenzoate dioxygenase genes (cbdSABC) involved in the degradation of benzoate and 2-halobenzoate in Burkholderia sp. TH2
Gene
262
137-145
2001
Burkholderia sp.
brenda
Francisco, P.B.; Ogawa, N.; Suzuki, K.; Miyashita, K.
The chlorobenzoate dioxygenase genes of Burkholderia sp. strain NK8 involved in the catabolism of chlorobenzoates
Microbiology
147
121-133
2001
Burkholderia sp., Burkholderia sp. NK8
brenda
Romanov, V.; Hausinger, R.P.
Pseudomonas aeruginosa 142 uses a three-component ortho-halobenzoate 1,2-dioxygenase for metabolism of 2,4-dichloro- and 2-chlorobenzoate
J. Bacteriol.
176
3368-3374
1994
Pseudomonas aeruginosa, Pseudomonas aeruginosa 142
brenda
Wittich, R.; Wolff, P.
Growth of the genetically engineered strain Cupriavidus necator RW112 with chlorobenzoates and technical chlorobiphenyls
Microbiology
153
186-195
2007
Burkholderia cepacia, Burkholderia cepacia 2CBS
brenda
Baggi, G.; Bernasconi, S.; Zangrossi, M.; Cavalca, L.; Andreoni, V.
Co-metabolism of di- and trichlorobenzoates in a 2-chlorobenzoate-degrading bacterial culture: Effect of the position and number of halo-substituents
Int. Biodeter. Biodegrad.
62
57-64
2008
Cupriavidus necator (A8YPA5), Stenotrophomonas maltophilia (A8YPA6)
-
brenda
Xu, C.; Zang, X.; Hang, X.; Liu, X.; Yang, H.; Liu, X.; Jiang, J.
Degradation of three monochlorobenzoate isomers by different bacteria isolated from a contaminated soil
Int. Biodeterior. Biodegrad.
120
192-202
2017
Pseudomonas sp. 2-CBA
-
brenda