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IUBMB Comments Requires Fe2+ and ascorbate. The enzyme, characterized from an uncultured marine bacterium, is involved in a (2-aminoethyl)phosphonate degradation pathway.
The enzyme appears in viruses and cellular organisms
Synonyms phnY , more
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phnY
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(2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (2-amino-1-hydroxyethyl)phosphonate + succinate + CO2
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MetaCyc
2-aminoethylphosphonate degradation III
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(2-aminoethyl)phosphonate,2-oxoglutarate:oxygen oxidoreductase (1-hydroxylating)
Requires Fe2+ and ascorbate. The enzyme, characterized from an uncultured marine bacterium, is involved in a (2-aminoethyl)phosphonate degradation pathway.
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(2-aminoethyl)phosphonate + 2-oxoglutarate + O2
(2-amino-1-hydroxyethyl)phosphonate + succinate + CO2
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(2-aminoethyl)phosphonate + 2-oxoglutarate + O2
(2-amino-1-hydroxyethyl)phosphonate + succinate + CO2
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Substrates: - Products: -
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Highest Expressing Human Cell Lines
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PHNY_UNCHF
262
0
30264
Swiss-Prot
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affinity column chromatography
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expressed in Escherichia coli BL21(DE3) cells
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McSorley, F.R.; Wyatt, P.B.; Martinez, A.; DeLong, E.F.; Hove-Jensen, B.; Zechel, D.L.
PhnY and PhnZ comprise a new oxidative pathway for enzymatic cleavage of a carbon-phosphorus bond
J. Am. Chem. Soc.
134
8364-8367
2012
Escherichia coli
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