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Information on EC 1.14.11.36 - pentalenolactone F synthase

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IUBMB Comments
Requires Fe(II) and ascorbate. Isolated from the bacteria Streptomyces exfoliatus, Streptomyces arenae and Streptomyces avermitilis. Part of the pentalenolactone biosynthesis pathway.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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Synonyms
penD, pntD, ptlD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pentalenolactone D + 2 2-oxoglutarate + 2 O2 = pentalenolactone F + 2 succinate + 2 CO2 + H2O
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overall reaction
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pentalenolactone D + 2-oxoglutarate + O2 = pentalenolactone E + succinate + CO2 + H2O
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(1a)
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pentalenolactone E + 2-oxoglutarate + O2 = pentalenolactone F + succinate + CO2
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(1b)
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