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Information on EC 1.14.11.32 - codeine 3-O-demethylase

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IUBMB Comments
Requires Fe2+. Catalyses a step in morphine biosynthesis. The enzyme also catalyses the 3-O-demethylation of thebaine to oripavine, with lower efficiency.
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The expected taxonomic range for this enzyme is: Papaver
Synonyms
codeine O-demethylase, codeine-O-demethylase, CODM, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
codeine + 2-oxoglutarate + O2 = morphine + formaldehyde + succinate + CO2
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