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Information on EC 1.14.11.31 - thebaine 6-O-demethylase

for references in articles please use BRENDA:EC1.14.11.31
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EC Tree
IUBMB Comments
Requires Fe2+. Catalyses a step in morphine biosynthesis. The product neopinione spontaneously rearranges to the more stable codeinone. The enzyme also catalyses the 6-O-demethylation of oripavine to morphinone, with lower efficiency.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
T6ODM, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
thebaine + 2-oxoglutarate + O2 = neopinone + formaldehyde + succinate + CO2
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