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Information on EC 1.13.11.19 - cysteamine dioxygenase

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IUBMB Comments
A non-heme iron protein that is involved in the biosynthesis of taurine. Requires catalytic amounts of a cofactor-like compound, such as sulfur, sufide, selenium or methylene blue for maximal activity. 3-Aminopropanethiol (homocysteamine) and 2-mercaptoethanol can also act as substrates, but glutathione, cysteine, and cysteine ethyl- and methyl esters are not good substrates [1,3].
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The enzyme appears in viruses and cellular organisms
Synonyms
cysteamine dioxygenase, 2-aminoethanethiol dioxygenase, cysteamine oxygenase, persulfurase, gm237, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-aminoethanethiol + O2 = hypotaurine
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PATHWAY SOURCE
PATHWAYS
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