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Information on EC 1.12.1.4 - hydrogenase (NAD+, ferredoxin)

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IUBMB Comments
The enzyme from Thermotoga maritima contains a [FeFe] cluster (H-cluster) and iron-sulfur clusters. It works in the direction evolving hydrogen as a means of eliminating excess reducing equivalents.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
iron hydrogenase, [fefe]-type hydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 H2 + NAD+ + 2 oxidized ferredoxin = 5 H+ + NADH + 2 reduced ferredoxin
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PATHWAY SOURCE
PATHWAYS
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